PDF(Pubmed)
Abstract：
UNASSIGNED: Cryptoccous infection or cryptococcosis is a severe opportunistic infection occurring mainly in immunocompromised patients. Laryngeal cryptococcus infection is rare. In an immunocompetent patient, inhaled corticosteroid was reported to be a possible risk factor.
METHODS: We discuss a case of right vocal fold cryptococcus infection in a healthy, immunocompetent 71-year-old man with no history of inhaled corticosteroid, presented with hoarseness and intermittent aspiration symptom for 1 year duration. Further examination showed right anterior vocal fold mass with presence of right vallecular cyst.
UNASSIGNED: Patient underwent direct laryngoscopy, excision of right vocal fold mass and marsupialization of vallecular cyst. Histopathological examination revealed cryptococcal infection. Patient subsequently treated with oral fluconazole 400 mg daily for 6 months. To date, hoarseness and aspiration symptoms have resolved.
CONCLUSIONS: We are sharing our experience in managing laryngeal cryptococcus infection in an immunocompetent patient where the associated risk factors discussed in previous literatures are absent.
METHODS: We discuss a case of right vocal fold cryptococcus infection in a healthy, immunocompetent 71-year-old man with no history of inhaled corticosteroid, presented with hoarseness and intermittent aspiration symptom for 1 year duration. Further examination showed right anterior vocal fold mass with presence of right vallecular cyst.
UNASSIGNED: Patient underwent direct laryngoscopy, excision of right vocal fold mass and marsupialization of vallecular cyst. Histopathological examination revealed cryptococcal infection. Patient subsequently treated with oral fluconazole 400 mg daily for 6 months. To date, hoarseness and aspiration symptoms have resolved.
CONCLUSIONS: We are sharing our experience in managing laryngeal cryptococcus infection in an immunocompetent patient where the associated risk factors discussed in previous literatures are absent.
摘要：
■隐球菌感染或隐球菌病是一种严重的机会性感染，主要发生在免疫功能低下的患者中。喉隐球菌感染罕见。在一个有免疫能力的患者中，据报道,吸入皮质类固醇是一个可能的危险因素.
方法：我们讨论了一例健康的右声带隐球菌感染，免疫功能正常的71岁男性，无吸入皮质类固醇病史，出现声音嘶哑和间歇性误吸症状持续1年。进一步检查显示右前声带肿块，存在右瓣膜囊肿。
■患者接受了直接喉镜检查，右声带肿块切除术及囊状囊肿有袋化。组织病理学检查显示隐球菌感染。患者随后每天口服氟康唑400mg治疗6个月。迄今为止,声音嘶哑和误吸症状已经解决。
结论：我们正在分享我们在一名免疫功能正常的患者中管理喉隐球菌感染的经验，该患者没有先前文献中讨论的相关危险因素。
方法：我们讨论了一例健康的右声带隐球菌感染，免疫功能正常的71岁男性，无吸入皮质类固醇病史，出现声音嘶哑和间歇性误吸症状持续1年。进一步检查显示右前声带肿块，存在右瓣膜囊肿。
■患者接受了直接喉镜检查，右声带肿块切除术及囊状囊肿有袋化。组织病理学检查显示隐球菌感染。患者随后每天口服氟康唑400mg治疗6个月。迄今为止,声音嘶哑和误吸症状已经解决。
结论：我们正在分享我们在一名免疫功能正常的患者中管理喉隐球菌感染的经验，该患者没有先前文献中讨论的相关危险因素。
