PDF(Pubmed)
Abstract：
This review paper highlights the trans-dermic delivery of nanoparticles (NPs) based antifungal ointments with the help of nanotechnology. It also describes the novel trans-dermal approach utilizing various nanoparticles which enables an efficient delivery to the target site. This current review gives an overview about past research and developments as well as the current nanoparticle-based ointments. This review also presents data regarding types, causes of infection, and different pathogens within their infection site. It also gives information about antifungal ointments with their activity and side effects of antifungal medicines. Additionally, this review also focuses on the future aspects of the topical administration of nanoparticle-based antifungal ointments. These nanoparticles can encapsulate multiple antifungal drugs as a combination therapy targeting different aspects of fungal infection. Nanoparticles can be designed in such a way that they can specifically target fungal cells and do not affect healthy cells. Nanoparticle based antifungal ointments exhibit outstanding potential to treat fungal diseases. As further research and advancements evolve in nanotechnology, we expect more development of nanoparticle-based antifungal formulations shortly. This paper discusses all the past and future applications, recent trends, and developments in the various field and also shows its bright prospective in the upcoming years.
摘要：
这篇综述论文重点介绍了在纳米技术的帮助下，基于纳米颗粒（NPs）的抗真菌软膏的经皮递送。它还描述了利用各种纳米颗粒的新的经皮方法,其能够有效地递送到目标部位。这篇综述概述了过去的研究和发展以及当前的纳米颗粒软膏。这篇评论还提供了有关类型的数据，感染的原因，和感染部位的不同病原体。它还提供有关抗真菌软膏的信息，以及抗真菌药物的活性和副作用。此外,本综述还重点介绍了基于纳米颗粒的抗真菌软膏的局部给药的未来方面。这些纳米颗粒可以封装多种抗真菌药物，作为靶向真菌感染不同方面的联合疗法。纳米颗粒可以以这样的方式设计,即它们可以特异性地靶向真菌细胞并且不影响健康细胞。基于纳米颗粒的抗真菌软膏显示出治疗真菌疾病的突出潜力。随着纳米技术的进一步研究和进步，我们预计更多的纳米颗粒为基础的抗真菌制剂的发展很快。本文讨论了过去和未来的所有应用，最近的趋势,以及各个领域的发展，也显示出未来几年的光明前景。
