PDF(Pubmed)
Abstract：
Adamantinoma, an uncommon low-grade primary malignant bone tumor, rarely causes leg pain in adolescents and typically manifests in the lower extremities, with a notable preference for the tibia, although occurrences in other bones such as the femur, fibula, and pelvis have been documented. Instances of local recurrence and regional metastasis are infrequent. This case report aims to comprehensively review the clinical presentation, imaging features, histological findings, and management of adamantinoma. The presented case involves a 17-year-old male patient with a four-year history of edema and discomfort in the right anterior leg. Radiographic examination of the proximal tibia revealed a well-defined, expansile lytic-sclerotic lesion with multiple septae and a partially sclerotic border. Subsequent magnetic resonance imaging (MRI) confirmed the nature of the lesion, and a biopsy, followed by histological analysis, confirmed the diagnosis of adamantinoma. This case highlights the significance of a multidisciplinary approach, emphasizing close collaboration among radiology, pathology, and orthopedic oncology in adamantinoma management. Long-term follow-up is imperative for monitoring recurrence and administering timely therapy. The objective of this case report is to contribute to an improved understanding of adamantinoma and offer guidance on the treatment of this uncommon bone tumor.
摘要：
Adamantinoma,罕见的低度原发性恶性骨肿瘤，青少年很少引起腿部疼痛，通常表现在下肢，明显偏爱胫骨，虽然发生在其他骨骼，如股骨，腓骨,和骨盆都有记录.局部复发和区域转移的情况很少见。本病例报告旨在全面回顾临床表现，成像特征,组织学发现，和金刚烷瘤的管理。该病例涉及一名17岁的男性患者，有4年的右前腿水肿和不适史。胫骨近端影像学检查显示，扩张性溶血性硬化性病变，有多个隔膜和部分硬化边界。随后的磁共振成像（MRI）证实了病变的性质，还有活检,然后进行组织学分析,确诊为金刚砂瘤。这个案例突出了多学科方法的重要性，强调放射科之间的密切合作，病理学,和整形外科肿瘤学在金刚砂瘤管理中的应用。长期随访对于监测复发和及时给予治疗至关重要。本病例报告的目的是促进对金刚烷胺瘤的了解，并为这种罕见的骨肿瘤的治疗提供指导。
