PDF(Pubmed)
Abstract：
Human herpes virus-6 (HHV-6) is a common cause of viral infection in humans, recognized for causing exanthema subitem during the first two years of life. Chronic inflammatory states in different autoimmune diseases can be associated with an immunosuppressed microenvironment. We report a case of HHV-6-associated meningitis in a patient with psoriasis. A 36-year-old man with a history of psoriasis presented with worsening bifrontal headache as well as painful oral lesions on the tongue and soft palate. Computed tomographic (CT) scan of the brain was nondiagnostic. Cerebrospinal fluid (CSF) analysis was diagnostic for HHV-6 infection and was treated with intravenous ganciclovir for two weeks. This case report highlights the emergence of HHV-6 infections in people with underlying mild immune disorders, such as psoriasis. Plaque psoriasis, such as in this patient, could be related to viral infections not typically seen among adults.
摘要：
人类疱疹病毒-6（HHV-6）是人类病毒感染的常见原因，被认为是在生命的头两年内引起激斑的子项目。不同自身免疫性疾病中的慢性炎症状态可能与免疫抑制的微环境有关。我们报告了一例牛皮癣患者的HHV-6相关脑膜炎。一名有牛皮癣病史的36岁男子表现为双额头痛恶化以及舌头和软腭的口腔疼痛病变。大脑的计算机断层扫描（CT）扫描无法诊断。脑脊液（CSF）分析可诊断HHV-6感染，并静脉注射更昔洛韦治疗两周。该病例报告强调了患有潜在轻度免疫疾病的人中HHV-6感染的出现，比如牛皮癣。斑块型银屑病,比如在这个病人身上，可能与成人中不常见的病毒感染有关。
