关键词: Adult Allergic Asthma Behavioral Case-control Determinants Environmental Ethiopia Tigray

Mesh : Adult Child Humans Case-Control Studies Ethiopia / epidemiology Asthma / epidemiology Hypersensitivity Dermatitis, Atopic Dust

来  源:   DOI:10.7717/peerj.16530   PDF(Pubmed)

Abstract:
UNASSIGNED: Asthma is a public health concern affecting millions of productive age groups. Several studies were conducted on the determinants of asthma in children. However, little is known about the determinants of asthma among adults in Ethiopia. Understanding the determinants of asthma among adults can help reduce its burden. This study was aimed at identifying determinant factors for developing asthma among adults in Tigray hospitals.
UNASSIGNED: A facility-based, unmatched case-control study design was conducted from January 1 to April 26, 2019. A total of 698 participants (228 cases and 470 controls) completed their guided interviews using structured and pretested questionnaires by trained data collectors. A modified standard questionnaire from the European Community Respiratory Health Survey II (ECRHS II) was used to collect the data. The case definition was patients having asthma, and the control definition was patients without asthma. Data were entered and cleaned using Epi Data Manager Version 3.1 software and imported to statistical packages for social sciences Version 25 software for analysis. To identify asthma determinants, bivariate and multivariable logistic regression models were fitted.
UNASSIGNED: The response rate for both cases and controls was 95.9%. The odds of developing asthma was nearly twice higher among those who resided in urban (AOR = 1.68; 95% CI [1.13-2.50]), more than twice higher among those who have income less than 1000 ETB (AOR = 2.3; 95% CI [1.17-4.56]), twice higher among those who had history of skin allergy (AOR = 2.09; 95% CI [1.14-3.86]), over four times higher among those with family history of asthma (AOR = 4.26; 95% CI [2.63-6.91]), three times higher among those having house dust or smoke exposure (AOR = 3.01; 95% CI [1.96-4.64]), over five times higher among those lifetime firewood users (AOR = 5.39; 95% CI [3.34-8.72]), door opening while cooking (AOR = 0.35; 95% CI [0.26-0.55]), nearly two times higher among those having house dampness (AOR = 1.98; 95% CI [1.069-3.68]), over seven times higher among pet owners (AOR = 7.46; 95% CI [4.04-13] and almost twice higher among those who were physically inactive (AOR = 1.75; 95% CI [1.11-2.85]).
UNASSIGNED: Asthma has been associated with urbanization, low income, a history of allergic diseases, indoor smoke or dust, firewood use, pet ownership, and a sedentary lifestyle. The community should be informed about the known risks and implement preventive steps like opening a door while cooking to lower the risk of asthma.
摘要:
哮喘是影响数百万生产年龄组的公共卫生问题。对儿童哮喘的决定因素进行了几项研究。然而,对埃塞俄比亚成年人哮喘的决定因素知之甚少。了解成人哮喘的决定因素有助于减轻其负担。这项研究旨在确定Tigray医院成人发生哮喘的决定因素。
基于设施的,无匹配的病例对照研究设计于2019年1月1日至4月26日进行.共有698名参与者(228个案例和470个对照)使用训练有素的数据收集者的结构化和预先测试的问卷完成了他们的指导访谈。使用欧洲共同体呼吸健康调查II(ECRHSII)的改良标准问卷收集数据。病例定义是哮喘患者,对照定义为无哮喘患者.使用Epi数据管理器3.1版软件输入和清理数据,并导入到社会科学25版软件的统计包中进行分析。为了确定哮喘的决定因素,拟合了双变量和多变量逻辑回归模型。
两种病例和对照的缓解率为95.9%。居住在城市的人患哮喘的几率几乎高出两倍(AOR=1.68;95%CI[1.13-2.50])。收入低于1000ETB的人高出两倍以上(AOR=2.3;95%CI[1.17-4.56]),在有皮肤过敏病史的人群中高出两倍(AOR=2.09;95%CI[1.14-3.86]),在有哮喘家族史的人群中高出4倍以上(AOR=4.26;95%CI[2.63-6.91]),房屋灰尘或烟雾暴露者高出三倍(AOR=3.01;95%CI[1.96-4.64]),在那些终身木柴使用者中,高出五倍以上(AOR=5.39;95%CI[3.34-8.72]),烹饪时开门(AOR=0.35;95%CI[0.26-0.55]),房屋潮湿的人群高出近两倍(AOR=1.98;95%CI[1.069-3.68]),宠物主人比宠物主人高出7倍以上(AOR=7.46;95%CI[4.04-13],身体不活动者高出近2倍(AOR=1.75;95%CI[1.11-2.85])。
哮喘与城市化有关,低收入,有过敏性疾病史,室内烟雾或灰尘,木柴使用,宠物所有权,和久坐不动的生活方式。应告知社区已知的风险,并实施预防措施,例如在烹饪时打开门,以降低哮喘的风险。
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