Abstract:
Alzheimer\'s, Parkinson\'s, and dementia are the leading neurodegenerative diseases that threaten the world with the aging population. Although the pathophysiology of each disease is unique, the steps to be taken to prevent diseases are similar. One of the changes that a person can make alone is to gain the habit of an antioxidant-rich diet. Phytochemicals known for their antioxidant properties have been reported to prevent neurodegenerative diseases in various studies. Phytochemicals with similar chemical structures are grouped. Accordingly, there are two main groups of phytochemicals, flavonoid and non-flavonoid. Various in vitro and in vivo studies on phytochemicals have proven neuroprotective effects by increasing cognitive function with their anti-inflammatory and antioxidant mechanisms. The purpose of this review is to summarize the in vitro and in vivo studies on phytochemicals with neuroprotective effects and to provide insight.
摘要:
老年痴呆症,帕金森,痴呆症是随着人口老龄化而威胁世界的主要神经退行性疾病。尽管每种疾病的病理生理学都是独特的,预防疾病的步骤是相似的。一个人可以独自做出的改变之一是养成富含抗氧化剂的饮食习惯。已经报道了以其抗氧化特性而闻名的植物化学物质在各种研究中预防神经退行性疾病。具有相似化学结构的植物化学品被分组。因此,有两种主要的植物化学物质,类黄酮和非类黄酮。对植物化学物质的各种体外和体内研究已证明通过增加认知功能及其抗炎和抗氧化机制具有神经保护作用。这篇综述的目的是总结具有神经保护作用的植物化学物质的体外和体内研究,并提供见解。