PDF(Pubmed)
Abstract：
UNASSIGNED: To report and review infantile orbital abscess caused by methicillin-resistant Staphylococcus aureus (MRSA).
UNASSIGNED: We report a case of MRSA-induced infantile orbital abscess accompanied by sepsis, pneumonia, and purulent meningitis. We systematically review cases of MRSA-induced infantile orbital abscess published in PubMed, Web of Science and ScienceDirect until April 2023.
UNASSIGNED: We reviewed 14 patients [our patient + 13 patients (10 papers) identified via literature searches]. There were nine boys and five girls; nine neonates and five older infants; and 8 full-term births and 1 preterm birth. The gestational age at birth was unknown for five infants. The right and left orbits were affected in 10 and 4 patients, respectively. The clinical presentation included periorbital soft-tissue edema or redness (11 patients), fever (7 patients), exophthalmos (10 patients), limited eye movement (4 patients), purulent eye secretions (2 patients), and skin abscess and convulsion (1 patient each). The source of infection was sinusitis (8 patients), vertical transmission, gingivitis, dacryocystitis, upper respiratory tract infection (1 patient each), and unknown (2 patients). MRSA was detected in blood (6 patients) or pus culture (8 patients). Vancomycin or linezolid were used for 11 patients; corticosteroids were administered to only 1 patient. Surgical drainage was performed for 13 infants (external drainage, 11 patients; endoscopic drainage, 2 patients). Two patients initially had pulmonary and intracranial infections. Except for one patient with neurological dysfunction at discharge, all other infants had no sequelae or complications.
UNASSIGNED: Early aggressive anti-infective treatment and timely drainage are essential for managing MRSA-induced infantile orbital abscess.
UNASSIGNED: We report a case of MRSA-induced infantile orbital abscess accompanied by sepsis, pneumonia, and purulent meningitis. We systematically review cases of MRSA-induced infantile orbital abscess published in PubMed, Web of Science and ScienceDirect until April 2023.
UNASSIGNED: We reviewed 14 patients [our patient + 13 patients (10 papers) identified via literature searches]. There were nine boys and five girls; nine neonates and five older infants; and 8 full-term births and 1 preterm birth. The gestational age at birth was unknown for five infants. The right and left orbits were affected in 10 and 4 patients, respectively. The clinical presentation included periorbital soft-tissue edema or redness (11 patients), fever (7 patients), exophthalmos (10 patients), limited eye movement (4 patients), purulent eye secretions (2 patients), and skin abscess and convulsion (1 patient each). The source of infection was sinusitis (8 patients), vertical transmission, gingivitis, dacryocystitis, upper respiratory tract infection (1 patient each), and unknown (2 patients). MRSA was detected in blood (6 patients) or pus culture (8 patients). Vancomycin or linezolid were used for 11 patients; corticosteroids were administered to only 1 patient. Surgical drainage was performed for 13 infants (external drainage, 11 patients; endoscopic drainage, 2 patients). Two patients initially had pulmonary and intracranial infections. Except for one patient with neurological dysfunction at discharge, all other infants had no sequelae or complications.
UNASSIGNED: Early aggressive anti-infective treatment and timely drainage are essential for managing MRSA-induced infantile orbital abscess.
摘要：
■报告和回顾由耐甲氧西林金黄色葡萄球菌（MRSA）引起的婴儿眼眶脓肿。
■我们报告一例MRSA诱发的婴儿眼眶脓肿伴败血症，肺炎,和化脓性脑膜炎.我们系统地回顾了发表在PubMed，WebofScienceandScienceDirect至2023年4月。
■我们回顾了通过文献检索确定的14例患者[我们的患者+13例患者（10篇论文）]。有9个男孩和5个女孩；9个新生儿和5个较大的婴儿；8个足月分娩和1个早产。五名婴儿的出生胎龄未知。10例和4例患者的左右轨道受累，分别。临床表现包括眶周软组织水肿或红肿（11例），发烧（7名患者），突眼（10例），眼球运动受限（4名患者），脓性眼部分泌物（2例），皮肤脓肿和抽搐（各1例）。感染源是鼻窦炎（8例），垂直传动,牙龈炎,泪囊炎,上呼吸道感染（每人1例），未知（2名患者）。在血液（6例）或脓液培养（8例）中检测到MRSA。万古霉素或利奈唑胺用于11例患者;皮质类固醇仅用于1例患者。对13名婴儿进行了外科引流（外部引流，11例患者；内镜引流，2名患者）。两名患者最初患有肺部和颅内感染。除了一名出院时出现神经功能障碍的病人,所有其他婴儿均无后遗症或并发症。
■早期积极的抗感染治疗和及时的引流对于管理MRSA引起的婴儿眼眶脓肿至关重要。
■我们报告一例MRSA诱发的婴儿眼眶脓肿伴败血症，肺炎,和化脓性脑膜炎.我们系统地回顾了发表在PubMed，WebofScienceandScienceDirect至2023年4月。
■我们回顾了通过文献检索确定的14例患者[我们的患者+13例患者（10篇论文）]。有9个男孩和5个女孩；9个新生儿和5个较大的婴儿；8个足月分娩和1个早产。五名婴儿的出生胎龄未知。10例和4例患者的左右轨道受累，分别。临床表现包括眶周软组织水肿或红肿（11例），发烧（7名患者），突眼（10例），眼球运动受限（4名患者），脓性眼部分泌物（2例），皮肤脓肿和抽搐（各1例）。感染源是鼻窦炎（8例），垂直传动,牙龈炎,泪囊炎,上呼吸道感染（每人1例），未知（2名患者）。在血液（6例）或脓液培养（8例）中检测到MRSA。万古霉素或利奈唑胺用于11例患者;皮质类固醇仅用于1例患者。对13名婴儿进行了外科引流（外部引流，11例患者；内镜引流，2名患者）。两名患者最初患有肺部和颅内感染。除了一名出院时出现神经功能障碍的病人,所有其他婴儿均无后遗症或并发症。
■早期积极的抗感染治疗和及时的引流对于管理MRSA引起的婴儿眼眶脓肿至关重要。
