Abstract：
Coronary Artery Disease (CAD) represents a persistent global health menace, particularly prevalent in Eastern European nations. Often asymptomatic until its advanced stages, CAD can precipitate life-threatening events like myocardial infarction or stroke. While conventional risk factors provide some insight into CAD risk, their predictive accuracy is suboptimal. Amidst this, Coronary Calcium Scoring (CCS), facilitated by non-invasive computed tomography (CT), emerges as a superior diagnostic modality. By quantifying calcium deposits in coronary arteries, CCS serves as a robust indicator of atherosclerotic burden, thus refining risk stratification and guiding therapeutic interventions. Despite certain limitations, CCS stands as an instrumental tool in CAD management and in thwarting adverse cardiovascular incidents. This review delves into the pivotal role of CCS in CAD diagnosis and treatment, elucidates the involvement of calcium in atherosclerotic plaque formation, and outlines the principles and indications of utilizing CCS for predicting major cardiovascular events.
摘要：
冠状动脉疾病（CAD）代表了持续的全球健康威胁，在东欧国家尤其普遍。通常无症状直到晚期，CAD可以引发危及生命的事件，如心肌梗塞或中风。虽然传统的风险因素提供了对CAD风险的一些见解，他们的预测准确性是次优的。在此之中,冠状动脉钙评分（CCS），通过非侵入性计算机断层扫描（CT），作为一种优越的诊断方式出现。通过量化冠状动脉中的钙沉积，CCS是动脉粥样硬化负荷的有力指标，从而完善风险分层和指导治疗干预。尽管有一定的局限性,CCS是CAD管理和阻止不良心血管事件的工具。本文综述了CCS在CAD诊断和治疗中的关键作用。阐明钙参与动脉粥样硬化斑块的形成，并概述了利用CCS预测主要心血管事件的原理和适应症。
