Abstract：
gem-Dibromoalkanes are important synthetic building block in organic chemistry, but their preparation is still troublesome. Herein, we have developed a simple and practical protocol for the synthesis of gem-dibromoalkanes from aldehydes using tetrabutylammonium tribromide and triphenyl phosphite. A variety of alkyl and aromatic aldehydes can be transformed into the corresponding products within 10 minutes. This protocol is also applicable to alcohols, and the configuration of chiral alcohol is inverted during the process with excellent enantiopurity.
摘要：
宝石-二溴烷烃是有机化学中重要的合成结构单元，但是他们的准备仍然很麻烦。在这里，我们已经开发了一种简单实用的方案，使用四丁基三溴化铵和亚磷酸三苯酯从醛合成宝石-二溴烷烃。各种烷基和芳香醛可以在10分钟内转化为相应的产物。该协议也适用于酒精，并且在此过程中手性醇的构型被反转，具有优异的对映体纯度。
