PDF(Pubmed)
Abstract：
Bone development and lung function are integral to child and adolescent health. Both influence an individual\'s overall well-being and potentially affect long-term health. Utilizing a comprehensive dataset from the National Health and Nutrition Examination Survey, this study aims to elucidate the relationship between lung function and bone mineral density (BMD) in a representative sample of children and adolescents. The analysis covered 3410 participants aged 8 to 19 years. We employed weighted multivariate linear regression and restricted cubic spline curve visualizations to explore the intricate association between lung function metrics, particularly first-second expiratory volume 1 second/forced vital capacity ratio, and lumbar BMD. Our data indicated a positive association between lung function and lumbar BMD in children and adolescents. Specifically, higher lung function metrics were linked with increased lumbar BMD. This association was more pronounced in younger participants or those with a lower body mass index. A significant positive relationship exists between lung function and BMD in the pediatric population. Recognizing this association is crucial for holistic health strategies for children and adolescents. This study underscores the need for integrated health monitoring during formative years, which can influence health trajectories as these individuals transition to adulthood.
摘要：
骨发育和肺功能是儿童和青少年健康的组成部分。两者都会影响个人的整体幸福感，并可能影响长期健康。利用国家健康和营养调查的综合数据集，本研究旨在阐明儿童和青少年代表性样本中肺功能与骨密度(BMD)之间的关系.该分析涵盖了3410名8至19岁的参与者。我们采用加权多元线性回归和有限的三次样条曲线可视化来探索肺功能指标之间的复杂关联，特别是第一秒呼气量1秒/强制肺活量比，和腰椎BMD.我们的数据表明，儿童和青少年的肺功能与腰椎BMD之间存在正相关。具体来说,较高的肺功能指标与腰椎BMD升高相关.这种关联在年轻参与者或体重指数较低的参与者中更为明显。在儿科人群中，肺功能与BMD之间存在显着正相关。认识到这种关联对于儿童和青少年的整体健康战略至关重要。这项研究强调了在成长期间对综合健康监测的必要性，当这些个体过渡到成年期时，会影响健康轨迹。
