PDF(Pubmed)
Abstract：
We report a case of refractory acute myeloid leukemia with DEK-NUP214 rearrangement showing circulating monocytic blasts with abundant green cytoplasmic granules on the Wright-Giemsa stain. The granules were strongly positive for Perls\' Prussian blue, consistent with hemosiderin deposits. This previously unreported finding is suggestive of siderophage activity by leukemic blasts, likely associated with monocytic differentiation.
摘要：
我们报告了一例难治性急性髓细胞性白血病，伴有DEK-NUP214重排，显示循环中的单核细胞母细胞在Wright-Giemsa染色上具有丰富的绿色细胞质颗粒。颗粒对Perls\'普鲁士蓝呈强烈阳性，与含铁血黄素沉积物一致。这个以前未报道的发现提示白血病母细胞的铁皮细胞活动，可能与单核细胞分化有关。
