Abstract：
A systematic approach to collect, peruse, and summarize the available information relating to the potential benefits of consuming dietary microbes was pursued in this scoping review. This review focused on the research endpoints, experimental designs, and microbial exposure in experimental as well as observational research work. Using a structured- set of keywords, scientific databases were systematically searched to retrieve publications reporting outcomes pertaining to the use of dietary microbes in healthy, nonpatient populations. Searches were further tailored to focus on eight different health categories, namely, \"antibiotic associated diarrhoea\" (AAD), \"gastrointestinal health\" (GIH), \"immunological health\" (ImH), \"cardiovascular health and metabolic syndrome\" (CvHMS), \"cancer prevention\" (CanPr), \"respiratory health\" (ReH), \"weight management\" (WtMgt), and \"urogenital health\" (UrGH). Quality of evidence available in each publication was assessed using the Jadad scoring system. The search yielded 228 relevant publications describing 282 experimental cases comprising 62 research endpoints overall. A microbial dose of ≥ 2 × 10 9 $\\ge 2\\times 10^9$ CFU.day-1 was associated with non-negative reported outcomes. Older population groups with a median age of 39 years were associated with positive outcomes. More high-quality research is required investigating the role of dietary microbes in maintaining general health, particularly in the health categories of UrGH, WtMgt, and CanPr.
摘要：
一种系统的收集方法，细读,并总结了有关食用膳食微生物的潜在益处的现有信息。这篇综述集中在研究终点，实验设计,和微生物暴露在实验和观察研究工作中。使用一组结构化的关键字，对科学数据库进行了系统搜索，以检索报告与健康饮食中使用饮食微生物有关的结果的出版物，非患者人群。进一步针对八种不同的健康类别进行了搜索，即,“抗生素相关性腹泻”(AAD)，“胃肠道健康”（GIH），“免疫健康”（ImH），“心血管健康和代谢综合征”（CvHMS），“癌症预防”(CanPr)，“呼吸健康”(ReH)，“体重管理”(WtMgt)，和“泌尿生殖系统健康”(UrGH)。使用Jadad评分系统评估每个出版物中可用的证据质量。搜索产生了228个相关出版物，描述了282个实验案例，包括总共62个研究终点。微生物剂量≥2×109$\\ge2\\乘以10^9$CFU。第1天与非阴性报告结局相关.中位年龄为39岁的老年人群与阳性结果相关。需要更多高质量的研究来调查膳食微生物在维持整体健康中的作用。特别是在UrGH的健康类别中，WtMgt,CanPr.
