PDF(Pubmed)
Abstract：
UNASSIGNED: Japanese Spotted Fever (JSF) is a Spotted Fever Group (SFG) rickettsiosis caused by Rickettsia japonica. More than 300 cases are diagnosed annually in Japan, and the number of reported cases has been increasing. Correct diagnoses depend on the triad of symptoms and signs, including fever, rash, and eschar, which can be seen at the site of vector bites. JSF is not life-threatening if treated appropriately without diagnostic delay but there are some fatal cases every year. This negligence leads to disseminated intravascular coagulation (DIC) and multiple organ failure (MOF), and poor prognoses, consequently. Prompt diagnosis of JSF is difficult when the aforementioned triad of signs and symptoms is not initially present.
UNASSIGNED: This report describes three JSF cases: an 87-year-old woman with fever, shock, pancytopenia, DIC, and MOF; a 79-year-old man with fever and difficulty in movement; and a 78-year-old man with fever, general fatigue, and appetite loss. All patients had a rash and eschar, which led to prompt diagnosis and appropriate treatment immediately. All patients were treated without any complications.
UNASSIGNED: As mentioned above, JFS can be fatal with delayed diagnoses and treatment initiations. The key for a prompt diagnosis is to recognize the triad of symptoms and signs, which are not often present initially, and it makes JSF diagnosis challenging. Repeated comprehensive physical examinations are essential for prompt diagnosis and improve prognosis of JSF.
UNASSIGNED: This report describes three JSF cases: an 87-year-old woman with fever, shock, pancytopenia, DIC, and MOF; a 79-year-old man with fever and difficulty in movement; and a 78-year-old man with fever, general fatigue, and appetite loss. All patients had a rash and eschar, which led to prompt diagnosis and appropriate treatment immediately. All patients were treated without any complications.
UNASSIGNED: As mentioned above, JFS can be fatal with delayed diagnoses and treatment initiations. The key for a prompt diagnosis is to recognize the triad of symptoms and signs, which are not often present initially, and it makes JSF diagnosis challenging. Repeated comprehensive physical examinations are essential for prompt diagnosis and improve prognosis of JSF.
摘要：
■日本斑点热（JSF）是由日本立克次体引起的斑点热组（SFG）立克次体病。日本每年诊断300多例，报告的病例数量一直在增加。正确的诊断取决于症状和体征的三合会，包括发烧,皮疹,和焦痂，可以在载体叮咬的部位看到。如果适当治疗而没有诊断延迟，JSF不会危及生命，但每年都有一些致命病例。这种疏忽导致弥散性血管内凝血（DIC）和多器官功能衰竭（MOF），糟糕的预后，因此。当最初不存在上述三联征的体征和症状时，很难及时诊断JSF。
■本报告描述了三个JSF病例：一名87岁的发热妇女，震惊,全血细胞减少症,DIC,和财政部;一名79岁发烧,行动不便的男子;和一名78岁发烧的男子,一般疲劳,和食欲减退。所有患者都有皮疹和焦痂，这导致了及时的诊断和适当的治疗。所有患者均未出现任何并发症。
■如上所述，JFS可能是致命的延迟诊断和治疗开始。及时诊断的关键是识别症状和体征的三合会，最初并不经常出现，这使得JSF诊断具有挑战性。反复的综合体检对于JSF的及时诊断和改善预后至关重要。
■本报告描述了三个JSF病例：一名87岁的发热妇女，震惊,全血细胞减少症,DIC,和财政部;一名79岁发烧,行动不便的男子;和一名78岁发烧的男子,一般疲劳,和食欲减退。所有患者都有皮疹和焦痂，这导致了及时的诊断和适当的治疗。所有患者均未出现任何并发症。
■如上所述，JFS可能是致命的延迟诊断和治疗开始。及时诊断的关键是识别症状和体征的三合会，最初并不经常出现，这使得JSF诊断具有挑战性。反复的综合体检对于JSF的及时诊断和改善预后至关重要。
