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Abstract：
The objective of this study was retrospectively to analyze the clinical characteristics and 18F-FDG PET/CT findings in Meigs syndrome (MS) patients. A total of 21 patients with MS induced by ovarian stromal tumors and 69 patients with pseudo-MS caused by ovarian cancer (OC-PMS) were subjected to evaluation using 18F-FDG PET/CT. Visual and semi-quantitative methods were employed to analyze the PET/CT findings. Visual analysis included recording whether the density of the primary tumor was uniform, whether there were cystic changes and calcifications, and the location of serous fluid accumulation. Semi-quantitative analysis involved the measurement of the tumor size, SUVmax, and SUVmean. No significant difference was observed in the size and density of primary tumors between the MS group and the OC-PMS group. However, the SUVmax and SUVmean of tumors in the MS group were found to be significantly lower than those in the OC-PMS group. The amount of serous cavity effusion caused by ovarian sex cord stromal tumors was found to be unrelated to the size of the tumor, SUVmax, and SUVmean but was positively correlated with the level of Ca125. MS patients have both benign ovarian tumors and ascites and/or pleural effusion, which may be accompanied by elevated Ca125 levels. This should be considered as one of the differential diagnoses for ovarian cancer. Understanding the PET/CT features of MS can facilitate the attainment of an accurate diagnosis before surgery.
摘要：
本研究的目的是回顾性分析Meigs综合征（MS）患者的临床特征和18F-FDGPET/CT表现。使用18F-FDGPET/CT对21例卵巢间质瘤诱发的MS和69例卵巢癌引起的假MS（OC-PMS）进行评估。采用视觉和半定量方法分析PET/CT表现。视觉分析包括记录原发肿瘤的密度是否均匀，是否有囊性改变和钙化，和浆液积聚的位置。半定量分析涉及肿瘤大小的测量，SUVmax,和SUVmean。在MS组和OC-PMS组之间的原发性肿瘤的大小和密度没有观察到显着差异。然而,MS组肿瘤的SUVmax和SUVmean显著低于OC-PMS组.发现卵巢性索间质瘤引起的浆膜腔积液的数量与肿瘤的大小无关，SUVmax,和SUVmean，但与Ca125水平呈正相关。MS患者既有良性卵巢肿瘤，又有腹水和/或胸腔积液，这可能伴随着升高的Ca125水平。这应该被认为是卵巢癌的鉴别诊断之一。了解MS的PET/CT特征可以促进在手术前获得准确的诊断。
