In 2017-2018, MToP was carried out in a total of 109 women by administering a combination of mifepristone (600 mg orally) and misoprostol (400 mcg orally). Serum/urine (LSUP - low sensitivity urine pregnancy test) hCG assessment and US examination were performed at pregnancy diagnosis and MToP follow-up.
At pregnancy diagnosis, there was a positive and medium strong correlation between serum hCG and size of the gestational sac - GS (R = 0.711; P 1,000 IU/L and LSUP test was always positive). In 5.5% of women (6/109), a subsequent surgical intervention was carried out including those with ongoing pregnancy (N = 5); missed abortion (N = 1) was treated by additional misoprostol, where surgical intervention was not necessary.
At pregnancy diagnosis, there is a positive and medium strong correlation between serum hCG and CRL. In MToP follow-up, a negative LSUP test enables reliable exclusion of ongoing pregnancy and missed abortion. In case of a positive LSUP test, US examination should be performed; however, surgical intervention should not be indicated solely on the basis of uterine cavity dilatation.
在2017-2018年,通过给予米非司酮(600mg口服)和米索前列醇(400mcg口服)的组合,对总共109名女性进行了MToP。在妊娠诊断和MToP随访时进行血清/尿液(LSUP-低敏感性尿液妊娠试验)hCG评估和US检查。
在诊断妊娠时,血清hCG与孕囊-GS大小呈正相关,且呈中等相关性(R=0.711;P1,000IU/L,LSUP检验始终为阳性).5.5%的妇女(6/109),随后进行了手术干预,包括那些正在怀孕的人(N=5);错过流产(N=1)通过额外的米索前列醇治疗,不需要手术干预的地方。
在诊断妊娠时,血清hCG与CRL呈正相关,呈中等强相关。在MToP随访中,LSUP检测阴性可以可靠地排除正在进行的妊娠和稽留流产.如果LSUP测试呈阳性,应该进行美国检查;然而,手术干预不应仅仅基于子宫腔扩张。