Abstract：
BACKGROUND: Fructus Choerospondiatis is the dried and mature fruit of Choerospondias axillaris (Roxb.) Burtt et Hill. It has been used for a long time in Tibetan and Mongolian medicine, first recorded in the ancient Tibetan medicine book \"Medicine Diagnosis of the King of the Moon\" in the early 8th century. Fructus Choerospondiatis shows multiple pharmacological activities, especially in treating cardiovascular diseases.
OBJECTIVE: This paper reviews the progress in research on the botanical characteristics, traditional uses, chemical constituents, pharmacological activity, clinical studies, and quality control of Fructus Choerospondiatis. This review aims to summarize current research and provide a reference for further development and utilization of Fructus Choerospondiatis resources.
METHODS: The sources for this review include the Pharmacopeia of the People\'s Republic of China (2020), theses, and peer-reviewed papers (in both English and Chinese). Theses and papers were downloaded from electronic databases including Web of Science, PubMed, SciFinder, Scholar, Springer, and China National Knowledge Infrastructure.The search terms used were \"Choerospondias axillaris\", \"C. axillaris\", \"Choerospondias axillaris (Roxb.) Burtt et Hill\", \"Fructus choerospondiatis\", \"Guangzao\", \"Lapsi\", and \"Lupsi\".
RESULTS: Fructus Choerospondiatis contains polyphenols, organic acids, amino acids, fatty acids, polysaccharides, and other chemical components. These ingredients contribute to its diverse pharmacological activities such as antioxidant activity, protection against myocardial ischemia-reperfusion injury, anti-myocardial fibrosis, heart rhythm regulation, anti-tumor, liver protection, and immunity enhancement. It also affects the central nervous system, with the ability to repair damaged nerve cells.
CONCLUSIONS: Fructus Choerospondiatis, with its various chemical compositions and pharmacological activities, is a promising medicinal resource. However, it remains under-researched, particularly in pharmacodynamic material basis and quality control. These areas require further exploration by researchers in the future.
OBJECTIVE: This paper reviews the progress in research on the botanical characteristics, traditional uses, chemical constituents, pharmacological activity, clinical studies, and quality control of Fructus Choerospondiatis. This review aims to summarize current research and provide a reference for further development and utilization of Fructus Choerospondiatis resources.
METHODS: The sources for this review include the Pharmacopeia of the People\'s Republic of China (2020), theses, and peer-reviewed papers (in both English and Chinese). Theses and papers were downloaded from electronic databases including Web of Science, PubMed, SciFinder, Scholar, Springer, and China National Knowledge Infrastructure.The search terms used were \"Choerospondias axillaris\", \"C. axillaris\", \"Choerospondias axillaris (Roxb.) Burtt et Hill\", \"Fructus choerospondiatis\", \"Guangzao\", \"Lapsi\", and \"Lupsi\".
RESULTS: Fructus Choerospondiatis contains polyphenols, organic acids, amino acids, fatty acids, polysaccharides, and other chemical components. These ingredients contribute to its diverse pharmacological activities such as antioxidant activity, protection against myocardial ischemia-reperfusion injury, anti-myocardial fibrosis, heart rhythm regulation, anti-tumor, liver protection, and immunity enhancement. It also affects the central nervous system, with the ability to repair damaged nerve cells.
CONCLUSIONS: Fructus Choerospondiatis, with its various chemical compositions and pharmacological activities, is a promising medicinal resource. However, it remains under-researched, particularly in pharmacodynamic material basis and quality control. These areas require further exploration by researchers in the future.
摘要：
背景：油嘴草是腋下油嘴草的干燥成熟果实（Roxb。)伯特和希尔。它在藏、蒙医药中已经使用了很长时间,最早记载于8世纪初的古代藏医书《月王的医学诊断》中。五味子具有多种药理活性，尤其是治疗心血管疾病。
目的：本文综述了植物学特征的研究进展，传统用途,化学成分，药理活性，临床研究,沙棘的质量控制。本综述旨在对目前的研究进行总结,为沙棘资源的进一步开发利用提供参考。
方法：本综述的来源包括中华人民共和国药典（2020）中国（2020），theses,和同行评审论文（中英文）。论文和论文是从包括WebofScience在内的电子数据库下载的，PubMed,SciFinder,学者,Springer,和中国国家知识基础设施。使用的搜索词是\"Choerospondiasaxillaris\"，\"C腋下\“，\“腋下的回声(Roxb。)BurttetHill\“，“海绵体”，\"广早\",\"Lapsi\",和“Lupsi”。
结果：沙棘含有多酚，有机酸,氨基酸,脂肪酸，多糖，和其他化学成分。这些成分有助于其多种药理活性，如抗氧化活性，保护心肌缺血再灌注损伤,抗心肌纤维化，心律调节,抗肿瘤，肝脏保护,和免疫增强。它还会影响中枢神经系统，有能力修复受损的神经细胞.
结论：松茸，其各种化学成分和药理活性，是一种很有前途的药用资源。然而,它仍然研究不足，特别是在药效物质基础和质量控制方面。这些领域需要研究人员在未来进一步探索。
目的：本文综述了植物学特征的研究进展，传统用途,化学成分，药理活性，临床研究,沙棘的质量控制。本综述旨在对目前的研究进行总结,为沙棘资源的进一步开发利用提供参考。
方法：本综述的来源包括中华人民共和国药典（2020）中国（2020），theses,和同行评审论文（中英文）。论文和论文是从包括WebofScience在内的电子数据库下载的，PubMed,SciFinder,学者,Springer,和中国国家知识基础设施。使用的搜索词是\"Choerospondiasaxillaris\"，\"C腋下\“，\“腋下的回声(Roxb。)BurttetHill\“，“海绵体”，\"广早\",\"Lapsi\",和“Lupsi”。
结果：沙棘含有多酚，有机酸,氨基酸,脂肪酸，多糖，和其他化学成分。这些成分有助于其多种药理活性，如抗氧化活性，保护心肌缺血再灌注损伤,抗心肌纤维化，心律调节,抗肿瘤，肝脏保护,和免疫增强。它还会影响中枢神经系统，有能力修复受损的神经细胞.
结论：松茸，其各种化学成分和药理活性，是一种很有前途的药用资源。然而,它仍然研究不足，特别是在药效物质基础和质量控制方面。这些领域需要研究人员在未来进一步探索。
