PDF(Pubmed)
Abstract：
Objective: To compare the morphological and quantitative changes in pathological myopia (PM) and the perioperative changes in posterior scleral reinforcement (PSR) using three-dimensional magnetic resonance images (3D MRI). Methods: A total of 49 patients with high myopia (HM; 98 eyes), 15 with pathological myopia (PM; 19 eyes), and 10 without high myopia (NORM; 20 eyes) were recruited between September 2019 and July 2021. The patients underwent measurements of refractive error and axial length, as well as 3D MRI of the eyeball. Python was used to analyze the 3D MRI images, calculate the vitreous volume, establish a topography of the height of the eyeball posterior surface, and calculate the rate of change in height (H). For the PM group undergoing PSR, changes in vitreous volume and the highest point of the eyeball posterior surface in four quadrants (temporal, subtemporal, nasal, and subnasal) were compared before and after PSR. Results: The vitreous volume was smaller in the NORM group compared to the HM and PM groups (p < 0.01). The PM group had a larger volume than the HM group (p < 0.01). The H for the PM group was higher than that of the NORM and HM groups (p < 0.01). After PSR in the PM group, the total vitreous volume, as well as the volume in the subnasal and supratemporal quadrants, decreased (p < 0.05). Additionally, the highest point of the eyeball\'s posterior surface was generally shifted to the upper nasal side. Finally, the shape and position of the scleral band after PSR were plotted. Conclusion: 3D MRI is capable of a quantitative description of the eyeball morphology in PM and PSR. It allows for precise calculations of changes in vitreous volume and the H of the posterior surface. It also facilitates a meticulous analysis of the specific details of the scleral band following PSR.
摘要：
目的:利用三维磁共振图像(3DMRI)比较病理性近视(PM)和后巩膜加固术(PSR)围手术期的形态学和定量变化。方法:高度近视患者49例(HM;98只眼),病理性近视15例（PM；19眼），在2019年9月至2021年7月期间招募了10只非高度近视(NORM;20只眼).患者接受屈光不正和眼轴长度的测量，以及眼球的3DMRI。Python被用来分析3DMRI图像，计算玻璃体体积,建立眼球后表面高度的地形，并计算高度变化率(H)。对于进行PSR的PM组，四个象限的玻璃体体积和眼球后表面最高点的变化(颞侧，亚时态,鼻部,和鼻下）在PSR前后进行比较。结果：与HM和PM组相比，NORM组的玻璃体体积较小（p<0.01）。PM组的体积大于HM组（p<0.01）。PM组的H高于NORM和HM组（p<0.01）。在PM组中的PSR之后，总玻璃体体积,以及鼻下和颞上象限的体积，下降(p<0.05)。此外,眼球后表面的最高点一般移动到上鼻侧。最后,绘制PSR后巩膜带的形状和位置。结论：3DMRI能够定量描述PM和PSR的眼球形态。它允许精确计算玻璃体体积和后表面H的变化。它还有助于对PSR后巩膜带的具体细节进行细致的分析。
