PDF(Pubmed)
Abstract：
UNASSIGNED: Tissue synthesis is extremely important for the attenuation of postoperative discomforts, as it keeps the tissues coapted, accelerates the healing process, and reduces the bleeding period of the surgical wound. Thus, this study aimed to systematically review the results of clinical trials that compared the use of cyanoacrylate with conventional sutures after third molars extraction.
UNASSIGNED: Searches were conducted on MEDLINE (via PubMed), Cochrane Central Registry of Controlled Trials (CENTRAL), Virtual Health Library (VHL), and Web of Science. Articles published up to February 20, 2022, were included. No restrictions were imposed on data or language of publication.
UNASSIGNED: A total of 8 studies (5 randomized controlled trials and 3 non-randomized comparative clinical studies) were included in this review and five studies were included in the meta-analysis, comprising 440 patients. The use of cyanoacrylate promoted better results in pain reduction in the first postoperative day when compared to the use of conventional suture (SMD: -1.01; 95%CI -1.90 to -0.12). Cyanoacrylate group promoted significant but borderline edema reduction compared to conventional sutures in the 7th postoperative day (SMD: -0.24, 95%CI -0.46 to -0.01, I2 = 0 %). For the trismus outcome, in all periods evaluated no differences were found between the groups.
UNASSIGNED: Although promising results, there is no high-quality evidence to suggest the use of cyanoacrylate was better than conventional sutures.
UNASSIGNED: Searches were conducted on MEDLINE (via PubMed), Cochrane Central Registry of Controlled Trials (CENTRAL), Virtual Health Library (VHL), and Web of Science. Articles published up to February 20, 2022, were included. No restrictions were imposed on data or language of publication.
UNASSIGNED: A total of 8 studies (5 randomized controlled trials and 3 non-randomized comparative clinical studies) were included in this review and five studies were included in the meta-analysis, comprising 440 patients. The use of cyanoacrylate promoted better results in pain reduction in the first postoperative day when compared to the use of conventional suture (SMD: -1.01; 95%CI -1.90 to -0.12). Cyanoacrylate group promoted significant but borderline edema reduction compared to conventional sutures in the 7th postoperative day (SMD: -0.24, 95%CI -0.46 to -0.01, I2 = 0 %). For the trismus outcome, in all periods evaluated no differences were found between the groups.
UNASSIGNED: Although promising results, there is no high-quality evidence to suggest the use of cyanoacrylate was better than conventional sutures.
摘要：
■组织合成对于减轻术后不适极为重要，因为它保持组织接合，加速愈合过程，减少手术伤口的出血时间。因此，本研究旨在系统回顾第三磨牙拔除后使用氰基丙烯酸酯与常规缝线的临床试验结果。
■在MEDLINE（通过PubMed）上进行了搜索，Cochrane中央控制试验登记处（CENTRAL），虚拟健康图书馆(VHL)和WebofScience。包括截至2022年2月20日发布的文章。对数据或出版语言没有施加任何限制。
■本综述共纳入8项研究（5项随机对照试验和3项非随机对照临床研究），5项研究纳入荟萃分析，440名患者。与使用常规缝线(SMD:-1.01;95CI-1.90至-0.12)相比,使用氰基丙烯酸酯在术后第一天促进疼痛减轻的效果更好。在术后第7天，与常规缝线相比，氰基丙烯酸酯组促进了显着但临界性水肿的减少（SMD：-0.24，95CI-0.46至-0.01，I2=0％）。对于三联子的结果，在所有评估期间,组间均未发现差异.
■虽然有希望的结果，没有高质量的证据表明使用氰基丙烯酸酯比传统缝线更好.
■在MEDLINE（通过PubMed）上进行了搜索，Cochrane中央控制试验登记处（CENTRAL），虚拟健康图书馆(VHL)和WebofScience。包括截至2022年2月20日发布的文章。对数据或出版语言没有施加任何限制。
■本综述共纳入8项研究（5项随机对照试验和3项非随机对照临床研究），5项研究纳入荟萃分析，440名患者。与使用常规缝线(SMD:-1.01;95CI-1.90至-0.12)相比,使用氰基丙烯酸酯在术后第一天促进疼痛减轻的效果更好。在术后第7天，与常规缝线相比，氰基丙烯酸酯组促进了显着但临界性水肿的减少（SMD：-0.24，95CI-0.46至-0.01，I2=0％）。对于三联子的结果，在所有评估期间,组间均未发现差异.
■虽然有希望的结果，没有高质量的证据表明使用氰基丙烯酸酯比传统缝线更好.
