PDF(Pubmed)
Abstract：
This case report discusses a complex medical scenario involving a 25-year-old female patient initially diagnosed with acute hepatitis A virus (HAV) who later developed symptoms indicative of autoimmune hepatitis (AIH). The transition from uncomplicated HAV to impending subacute hepatic failure and autoimmune overlap syndrome highlights the importance of vigilant monitoring and a comprehensive diagnostic approach. The patient\'s medical evaluation revealed autoantibodies, elevated IgG levels, and liver biopsy findings consistent with steatohepatitis. Management included immunosuppressive therapy, resulting in a positive treatment response. The phenomenon of AIH following acute HAV infection, though rare, remains a subject of medical interest and presents diagnostic and therapeutic challenges. Further research and clinical experience are needed to develop effective strategies for these infrequent cases.
摘要：
本病例报告讨论了一个复杂的医疗情况，涉及一名25岁的女性患者，最初被诊断患有急性甲型肝炎病毒（HAV），后来出现了指示自身免疫性肝炎（AIH）的症状。从简单的HAV过渡到即将发生的亚急性肝功能衰竭和自身免疫重叠综合征突出了警惕监测和全面诊断方法的重要性。病人的医学评估显示自身抗体,升高的IgG水平，肝活检结果与脂肪性肝炎一致。管理包括免疫抑制治疗，产生积极的治疗反应。急性HAV感染后的AIH现象，虽然罕见，仍然是医学兴趣的主题，并提出了诊断和治疗挑战。需要进一步的研究和临床经验来制定针对这些罕见病例的有效策略。
