Abstract：
Hypertension is highly prevalent and remains one of the most frequent and preventable causes of cardiovascular morbidity and mortality. Yet, suboptimal blood pressure control is common. Hypertension clinics might play an important role in improving target attainment, by targeting drug therapy adherence, improving guideline compliance and by involving pharmacists.
We aimed to characterize patient drug therapy adherence, prescriber guideline compliance and pharmacist interventions at the hypertension clinic.
A prospective observational study was performed at the hypertension clinic of a large, academic hospital. Adult Dutch-speaking patients were eligible for inclusion. Following data were collected: patient demographics, medication use, patient adherence to prescribed antihypertensive drug therapies according to the BAASIS tool and prescriber compliance to the 2018 European Society of Cardiology (ESC) hypertension guidelines.
A cohort of 108 patients was included with 51.9% male and aged 65 (IQR: 52-75) years. In total, 104 patients took at least 1 antihypertensive drug and 46 patients (44.2%) were classified as non-adherent with regard to their antihypertensive treatment; 82 patients (78.8%) had suboptimal blood pressure control. Compliance with the ESC guidelines was 66.3% prior to the consultation at the clinic and significantly increased to 77.9% thereafter (p = 0.0015). The clinical pharmacist performed a medication review for 27 patients with a total of 44 recommendations and an acceptance rate of 59.1%.
A visit to the multidisciplinary hypertension clinic improved prescriber guideline compliance and the use of single pill combinations. Involvement of a clinical pharmacist could be beneficial to further improve patient drug therapy adherence and guideline compliance.
We aimed to characterize patient drug therapy adherence, prescriber guideline compliance and pharmacist interventions at the hypertension clinic.
A prospective observational study was performed at the hypertension clinic of a large, academic hospital. Adult Dutch-speaking patients were eligible for inclusion. Following data were collected: patient demographics, medication use, patient adherence to prescribed antihypertensive drug therapies according to the BAASIS tool and prescriber compliance to the 2018 European Society of Cardiology (ESC) hypertension guidelines.
A cohort of 108 patients was included with 51.9% male and aged 65 (IQR: 52-75) years. In total, 104 patients took at least 1 antihypertensive drug and 46 patients (44.2%) were classified as non-adherent with regard to their antihypertensive treatment; 82 patients (78.8%) had suboptimal blood pressure control. Compliance with the ESC guidelines was 66.3% prior to the consultation at the clinic and significantly increased to 77.9% thereafter (p = 0.0015). The clinical pharmacist performed a medication review for 27 patients with a total of 44 recommendations and an acceptance rate of 59.1%.
A visit to the multidisciplinary hypertension clinic improved prescriber guideline compliance and the use of single pill combinations. Involvement of a clinical pharmacist could be beneficial to further improve patient drug therapy adherence and guideline compliance.
摘要：
背景：高血压非常普遍，并且仍然是心血管疾病发病率和死亡率的最常见和可预防的原因之一。然而，血压控制欠佳是常见的。高血压诊所可能在提高目标达成方面发挥重要作用，通过靶向药物治疗依从性，提高指南依从性，并让药剂师参与进来。
目的：我们旨在表征患者药物治疗依从性，高血压诊所的处方者指南依从性和药剂师干预措施。
方法：在一家大型高血压诊所进行了一项前瞻性观察性研究，学术医院。讲荷兰语的成年患者有资格入选。收集以下数据：患者人口统计学，药物使用,根据BAASIS工具,患者对处方降压药治疗的依从性和处方者对2018年欧洲心脏病学会(ESC)高血压指南的依从性.
结果：108名患者纳入队列，其中51.9%为男性，年龄65岁（IQR：52-75岁）。总的来说,104例患者服用了至少1种抗高血压药物，46例患者（44.2％）的抗高血压治疗被归类为非粘附性；82例患者（78.8％）的血压控制欠佳。在诊所咨询之前，对ESC指南的依从性为66.3％，此后显着提高至77.9％（p=0.0015）。临床药师对27例患者进行药物审查,共建议44例,接受率为59.1%。
结论：对多学科高血压诊所的访问改善了处方者指南的依从性和单一药丸组合的使用。临床药师的参与可能有利于进一步提高患者药物治疗依从性和指南依从性。
目的：我们旨在表征患者药物治疗依从性，高血压诊所的处方者指南依从性和药剂师干预措施。
方法：在一家大型高血压诊所进行了一项前瞻性观察性研究，学术医院。讲荷兰语的成年患者有资格入选。收集以下数据：患者人口统计学，药物使用,根据BAASIS工具,患者对处方降压药治疗的依从性和处方者对2018年欧洲心脏病学会(ESC)高血压指南的依从性.
结果：108名患者纳入队列，其中51.9%为男性，年龄65岁（IQR：52-75岁）。总的来说,104例患者服用了至少1种抗高血压药物，46例患者（44.2％）的抗高血压治疗被归类为非粘附性；82例患者（78.8％）的血压控制欠佳。在诊所咨询之前，对ESC指南的依从性为66.3％，此后显着提高至77.9％（p=0.0015）。临床药师对27例患者进行药物审查,共建议44例,接受率为59.1%。
结论：对多学科高血压诊所的访问改善了处方者指南的依从性和单一药丸组合的使用。临床药师的参与可能有利于进一步提高患者药物治疗依从性和指南依从性。
