PDF(Pubmed)
Abstract：
This meta-analysis evaluates the efficacy of silver alginate dressings (SAD) compared to standard gauze (SG) in enhancing wound healing and reducing scar formation post-mastectomy in patients with triple-negative breast cancer. From an initial pool of 1245 articles, five studies met the inclusion criteria. The analysis revealed that SAD significantly improve early wound healing 1 week post-mastectomy, as indicated by lower Redness, Edema, Ecchymosis, Discharge, and Approximation (REEDA) scales (I2 = 85%; Random: SMD: -7.08, 95% CI: -8.26 to -5.98, p < 0.01), compared to SG. Additionally, long-term scar outcomes measured by the Manchester Scar Scale (MSS) 5 months post-mastectomy showed a notable reduction in scar formation (I2 = 95%; Random: SMD: -12.97, 95% CI: -16.20 to -9.75, p < 0.01)) in the silver alginate group. The findings support the use of SAD in post-mastectomy care for triple-negative breast cancer patients but highlight the need for further research on long-term safety and cost-effectiveness.
摘要：
这项荟萃分析评估了海藻酸银敷料（SAD）与标准纱布（SG）相比，在三阴性乳腺癌患者的乳房切除术后增强伤口愈合和减少疤痕形成的功效。从最初的1245篇文章中，5项研究符合纳入标准.分析显示，SAD显着改善乳房切除术后1周的早期伤口愈合，如较低的红度所示，水肿,瘀斑,放电,和近似（REEDA）量表（I2=85％；随机：SMD：-7.08，95％CI：-8.26至-5.98，p<0.01），与SG相比。此外,通过曼彻斯特疤痕量表（MSS）测量的长期瘢痕结局在乳房切除术后5个月显示，海藻酸银组的瘢痕形成显着减少（I2=95％；随机：SMD：-12.97，95％CI：-16.20至-9.75，p<0.01）。研究结果支持在三阴性乳腺癌患者的乳房切除术后护理中使用SAD，但强调需要进一步研究长期安全性和成本效益。
