Abstract：
Male genital lichen sclerosus (MGLSc) typically impacts the external genitalia, resulting in balanitis, erectile pain, urination symptoms, and/or urinary retention. Urethral stricture develops in up to 20 % of these patients, which is usually found in the distal part of the urethra but can, in severe instances, impact the entire urethra and cause structural changes. Patients with skin lesions limited to the foreskin and partially extending to the glans can typically be cured by circumcision, but the recurrence rate of stricture is high when the glans or urethra is extensively involved. In the following case report, we describe a 45-year-old man with a history of MGLSc for 3 years and urethral stricture for 2 years, and these conditions remained untreated after circumcision. We emphasize that treatment with 5-aminolevulinic acid-induced photodynamic therapy (ALA-PDT) may further improve outcomes in such severe cases.
摘要：
男性生殖器硬化性苔藓（MGLSc）通常会影响外生殖器，导致龟头炎，勃起疼痛,排尿症状,和/或尿潴留。这些患者中有高达20%的患者出现尿道狭窄，通常在尿道的远端发现，但可以，在严重的情况下，影响整个尿道并引起结构变化。皮肤病变局限于包皮并部分延伸至龟头的患者通常可以通过包皮环切术治愈，但是当龟头或尿道广泛受累时，狭窄的复发率很高。在以下案例报告中，我们描述了一个45岁的男性，有3年的MGLSc病史和2年的尿道狭窄，这些情况在包皮环切术后仍未得到治疗。我们强调，5-氨基乙酰丙酸诱导的光动力疗法（ALA-PDT）治疗可进一步改善此类严重患者的预后。
