Abstract：
BACKGROUND: Lower urinary tract dysfunction (LUTD) is a common, troublesome condition that often negatively affects patients\' quality of life. Current literature has long been interested in how posterior tibial nerve stimulation (PTNS) can affect this condition.
OBJECTIVE: To extensively and systematically explore how PTNS affects LUTD based on the most recent systematic reviews.
METHODS: A systematic search was conducted in PubMed, Scopus, Web of Science, and Embase according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All the systematic reviews, with or without meta-analysis that assessed the effects of PTNS on LUTD were retrieved. The quality of the included studies was assessed using the Joanna Briggs Institute tool, and analysis was conducted using the Comprehensive Meta-Analysis version 3 tool.
RESULTS: From a total of 3077 citations, 20 systematic reviews entered this study, and 13 of them included meta-analysis. The population of studies varied vastly, for instance, some studies included only children or women while other focused on a specific pathology like multiple sclerosis-induced neurogenic LUTD. The majority of included studies reported an overall improvement in LUTD following percutaneous PTNS, although admitting that these results were derived from moderate to low-quality evidence.
CONCLUSIONS: The findings of this thorough umbrella review showed that the positive benefits of PTNS in treating LUTD are currently supported by low-quality evidence, and it is crucial to interpret them with great care.
OBJECTIVE: To extensively and systematically explore how PTNS affects LUTD based on the most recent systematic reviews.
METHODS: A systematic search was conducted in PubMed, Scopus, Web of Science, and Embase according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All the systematic reviews, with or without meta-analysis that assessed the effects of PTNS on LUTD were retrieved. The quality of the included studies was assessed using the Joanna Briggs Institute tool, and analysis was conducted using the Comprehensive Meta-Analysis version 3 tool.
RESULTS: From a total of 3077 citations, 20 systematic reviews entered this study, and 13 of them included meta-analysis. The population of studies varied vastly, for instance, some studies included only children or women while other focused on a specific pathology like multiple sclerosis-induced neurogenic LUTD. The majority of included studies reported an overall improvement in LUTD following percutaneous PTNS, although admitting that these results were derived from moderate to low-quality evidence.
CONCLUSIONS: The findings of this thorough umbrella review showed that the positive benefits of PTNS in treating LUTD are currently supported by low-quality evidence, and it is crucial to interpret them with great care.
摘要：
背景：下尿路功能障碍（LUTD）是一种常见的，麻烦的状况往往会对患者的生活质量产生负面影响。目前的文献长期以来一直关注胫骨后神经刺激（PTNS）如何影响这种情况。
目的：基于最新的系统评价，广泛而系统地探讨PTNS如何影响LUTD。
方法：在PubMed中进行了系统搜索，Scopus,WebofScience,并根据系统评价和荟萃分析指南的首选报告项目进行Embase。所有的系统审查，检索了评估PTNS对LUTD影响的有或没有荟萃分析。纳入研究的质量使用乔安娜·布里格斯研究所的工具进行评估，并使用综合荟萃分析3版工具进行分析。
结果：在总共3077次引用中，20篇系统综述进入了这项研究，其中13项纳入了荟萃分析。研究的人口变化很大，例如,一些研究仅包括儿童或女性,而另一些研究则集中于特定的病理,如多发性硬化症诱导的神经源性LUTD.大多数纳入的研究报告了经皮PTNS后LUTD的总体改善，尽管承认这些结果来自中等至低质量的证据。
结论：这项全面综述的结果表明，目前，低质量证据支持PTNS治疗LUTD的积极益处，仔细解读它们是至关重要的。
目的：基于最新的系统评价，广泛而系统地探讨PTNS如何影响LUTD。
方法：在PubMed中进行了系统搜索，Scopus,WebofScience,并根据系统评价和荟萃分析指南的首选报告项目进行Embase。所有的系统审查，检索了评估PTNS对LUTD影响的有或没有荟萃分析。纳入研究的质量使用乔安娜·布里格斯研究所的工具进行评估，并使用综合荟萃分析3版工具进行分析。
结果：在总共3077次引用中，20篇系统综述进入了这项研究，其中13项纳入了荟萃分析。研究的人口变化很大，例如,一些研究仅包括儿童或女性,而另一些研究则集中于特定的病理,如多发性硬化症诱导的神经源性LUTD.大多数纳入的研究报告了经皮PTNS后LUTD的总体改善，尽管承认这些结果来自中等至低质量的证据。
结论：这项全面综述的结果表明，目前，低质量证据支持PTNS治疗LUTD的积极益处，仔细解读它们是至关重要的。
