PDF(Pubmed)
Abstract：
UNASSIGNED: Engeletin (ENG) is a natural flavonoid compound known for its diverse physiological and pharmacological effects, such as anti-inflammatory, antioxidant, and immunomodulatory properties. It has garnered significant attention as a promising candidate for drug development.
UNASSIGNED: This article aims to comprehensively review the clinical application, pharmacological action, and potential mechanisms of ENG, while exploring its prospects in clinical pharmacology.
UNASSIGNED: We conducted a systematic search of PubMed, Science Direct, Google Scholar, Web of Science, Scopus, and MEDLINE for a thorough review of high-quality articles on the source, extraction, and application of ENG, or the primary active ingredient for improving bodily injuries.
UNASSIGNED: ENG exhibits significant potential in treating a variety of diseases across different systems, attributed to its anti-inflammatory, antioxidant, anti-tumor, and metabolic regulatory activities. These effects are linked to direct or indirect interactions with multiple pathways involving key molecules upstream and downstream.
UNASSIGNED: While ENG shows promise, its development requires further exploration. Future studies should focus on elucidating its mechanisms of action, identifying targets through clinical studies, and optimizing compounds for drug development. These research directions are crucial for advancing the development and application of flavonoids. This review underscores the significant research potential of ENG, paving the way for its application in diverse clinical settings.
UNASSIGNED: This article aims to comprehensively review the clinical application, pharmacological action, and potential mechanisms of ENG, while exploring its prospects in clinical pharmacology.
UNASSIGNED: We conducted a systematic search of PubMed, Science Direct, Google Scholar, Web of Science, Scopus, and MEDLINE for a thorough review of high-quality articles on the source, extraction, and application of ENG, or the primary active ingredient for improving bodily injuries.
UNASSIGNED: ENG exhibits significant potential in treating a variety of diseases across different systems, attributed to its anti-inflammatory, antioxidant, anti-tumor, and metabolic regulatory activities. These effects are linked to direct or indirect interactions with multiple pathways involving key molecules upstream and downstream.
UNASSIGNED: While ENG shows promise, its development requires further exploration. Future studies should focus on elucidating its mechanisms of action, identifying targets through clinical studies, and optimizing compounds for drug development. These research directions are crucial for advancing the development and application of flavonoids. This review underscores the significant research potential of ENG, paving the way for its application in diverse clinical settings.
摘要：
■Engeletin（ENG）是一种天然类黄酮化合物，以其多种生理和药理作用而闻名，如抗炎，抗氧化剂，和免疫调节特性。作为有希望的药物开发候选物，它已经引起了极大的关注。
■本文旨在全面回顾其临床应用，药理作用，以及ENG的潜在机制，同时探索其在临床药理学中的应用前景。
■我们对PubMed进行了系统搜索，科学直接，谷歌学者，WebofScience,Scopus,和MEDLINE对来源的高质量文章进行彻底审查，提取,和ENG的应用，或改善身体伤害的主要活性成分。
■ENG在治疗不同系统的各种疾病方面具有巨大的潜力，归因于它的抗炎作用，抗氧化剂，抗肿瘤，和代谢调节活动。这些效应与涉及上游和下游关键分子的多个途径的直接或间接相互作用有关。
■当ENG显示承诺时，它的发展需要进一步探索。未来的研究应侧重于阐明其作用机制，通过临床研究确定目标，并优化药物开发的化合物。这些研究方向对于推进黄酮类化合物的开发和应用至关重要。这篇综述强调了ENG的巨大研究潜力，为其在不同临床环境中的应用铺平了道路。
■本文旨在全面回顾其临床应用，药理作用，以及ENG的潜在机制，同时探索其在临床药理学中的应用前景。
■我们对PubMed进行了系统搜索，科学直接，谷歌学者，WebofScience,Scopus,和MEDLINE对来源的高质量文章进行彻底审查，提取,和ENG的应用，或改善身体伤害的主要活性成分。
■ENG在治疗不同系统的各种疾病方面具有巨大的潜力，归因于它的抗炎作用，抗氧化剂，抗肿瘤，和代谢调节活动。这些效应与涉及上游和下游关键分子的多个途径的直接或间接相互作用有关。
■当ENG显示承诺时，它的发展需要进一步探索。未来的研究应侧重于阐明其作用机制，通过临床研究确定目标，并优化药物开发的化合物。这些研究方向对于推进黄酮类化合物的开发和应用至关重要。这篇综述强调了ENG的巨大研究潜力，为其在不同临床环境中的应用铺平了道路。
