Abstract：
Strongyloides stercoralis is a zoonotic soil-transmitted nematode affecting mainly humans and dogs but identified also in non-human primates, cats and wild carnivores. It has a cosmopolitan distribution being endemic in tropical and subtropical areas. In Romania, the infection was reported on several occasions in dogs with low prevalence (3.5% -3.8%), assessed by coproscopy and it was confirmed in human patients with no travel history. A 2-year-old male Boston Terrier dog presented to a private clinic due to severe digestive problems, in July 2022. The animal had a long history of health problems. The dog was in a very bad clinical condition with severe abdominal pain, bloody diarrhea, and weight loss. Coproparasitological examinations using the saline flotation method and the modified Baermann\'s technique were done, both being negative. In addition, an intestinal biopsy was performed during the second endoscopy. Nematodes were collected and identified morphologically and molecularly confirmed. Histology revealed severe inflammation of the duodenal mucosa with areas of edema, necrosis, and hemorrhage, and in the intestinal glands, there were numerous nematodes suggesting a parasitic infection by Strongyloides spp. PCR followed by sequencing confirmed the infection with S. stercoralis. The dog was treated with a combination of oral fenbendazole and milbemycin oxime for 5 months. No relapse was observed 3 months after negativity was attained. This case describes a severe clinical infection by Strongyloides stercoralis in a domestic dog from Romania and the recovery after long-term treatment.
摘要：
类圆圆线虫是一种人畜共患的土壤传播的线虫，主要影响人类和狗，但在非人类灵长类动物中也被发现。猫和野生食肉动物。它在热带和亚热带地区具有世界性分布。在罗马尼亚,在低患病率（3.5％-3.8％）的狗中多次报告感染，通过共镜检查进行评估，并在没有旅行史的人类患者中得到证实。一只2岁的雄性波士顿梗犬因严重的消化问题被送到一家私人诊所，2022年7月。这种动物的健康问题由来已久。这只狗的临床状况非常糟糕，腹部严重疼痛，血性腹泻,和减肥。使用盐水浮选法和改良的Baermann\'s技术进行了共寄生虫学检查，两者都是负面的。此外,在第二次内窥镜检查期间进行了肠活检.收集线虫并在形态和分子上进行鉴定。组织学显示十二指肠粘膜严重炎症，水肿区域，坏死,出血，在肠腺中，有许多线虫，表明类线虫属寄生虫感染。PCR随后测序证实了胸骨链球菌的感染。用口服芬苯达唑和米尔贝霉素肟的组合治疗狗5个月。阴性后3个月未观察到复发。该病例描述了来自罗马尼亚的一只家犬中赤圆圆线虫的严重临床感染以及长期治疗后的恢复。
