METHODS: We enrolled 182 patients diagnosed with definite ISSNHL. The percentage of mild ISSNHL patients and that of patients experiencing no change were compared between the high-CAVI and low-CAVI groups. Age, initial and final pure-tone average (PTA) values, CAVI, presence or absence of vertigo, and medical histories were retrospectively reviewed and included in univariate and multivariate analyses.
RESULTS: The percentage of mild ISSNHL patients was smaller in the high-CAVI group than in the low-CAVI group, whereas the percentage of patients experiencing no change was smaller in the high-CAVI group than in the low-CAVI group, although patients in the high-CAVI group were significantly older than those in the low-CAVI group. The Cox proportional hazard model revealed that high CAVI, hypertension, younger age, and initial PTA <90 dB were associated with hearing improvement.
CONCLUSIONS: ISSNHL in patients with high CAVI was more severe but had a better prognosis than that in those with low CAVI. CAVI may help evaluate diseases of vascular and other etiologies, as well as ISSNHL.
方法:我们招募了182例确诊为明确ISSNHL的患者。在高CAVI和低CAVI组之间比较了轻度ISSNHL患者的百分比和没有变化的患者的百分比。年龄,初始和最终纯音平均(PTA)值,CAVI,是否存在眩晕,和病史进行回顾性分析,并纳入单变量和多变量分析.
结果:高CAVI组轻度ISSNHL患者的百分比小于低CAVI组,而高CAVI组未发生改变的患者百分比小于低CAVI组,尽管高CAVI组患者的年龄明显高于低CAVI组.Cox比例风险模型揭示了高CAVI,高血压,年龄较小,初始PTA<90dB与听力改善有关。
结论:与低CAVI患者相比,高CAVI患者的ISSNHL更严重,但预后更好。CAVI可能有助于评估血管疾病和其他病因,以及ISSNHL。