PDF(Pubmed)
Abstract：
Dengue fever is a prevalent viral disease caused by a single-stranded positive RNA virus belonging to the Flaviviridae family, genus flavivirus. It is characterized by fever, headache, myalgias, leukopenia, rash, and plasma leakage, which may progress to compensated or uncompensated shock and multi-organ failure. Liver involvement is a common feature of Dengue fever and is usually manifested by nausea, vomiting, abdominal discomfort, anorexia, hepatomegaly, and elevated serum transaminase levels. Severe disease is associated with laboratory parameters such as mean Platelet count < 20,000/mm, Aspartate Transaminase Levels >45 IU, and lymphocytes <1500. The Expanded Dengue Syndrome (EDS), a term coined by World Health Organization in 2012, refers to an atypical presentation of Dengue fever that manifests with generalized impacts on normal physiology. This case report presents a 29-year-old male with EDS who presented at a Tertiary Care Hospital in Karachi and died a week later due to liver failure.
摘要：
登革热是一种流行的病毒性疾病，由属于黄病毒科的单链阳性RNA病毒引起，黄病毒属。它的特点是发烧，头痛,肌痛,白细胞减少症,皮疹,和等离子体泄漏，可能进展为补偿或无补偿休克和多器官衰竭。肝脏受累是登革热的常见特征，通常表现为恶心，呕吐,腹部不适,厌食症,肝肿大,血清转氨酶水平升高.严重疾病与实验室参数有关，例如平均血小板计数<20,000/mm，天冬氨酸转氨酶水平>45IU，淋巴细胞<1500。扩大的登革热综合症（EDS），世界卫生组织在2012年提出的一个术语是指登革热的非典型表现,表现为对正常生理的普遍影响.该病例报告介绍了一名29岁的EDS男性，他在卡拉奇的三级护理医院就诊，一周后因肝功能衰竭死亡。
