Abstract：
OBJECTIVE: To investigate the spatial distribution characteristics of the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody, and to examine the correlation between the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody in Hunan Province in 2020, so as to provide insights into advanced schistosomiais control in the province.
METHODS: The epidemiological data of schistosomiasis in Hunan Province in 2020 were collected, including number of permanent residents in survey villages, number of advanced schistosomiasis patients, number of residents receiving serological tests and number of residents seropositive for anti-Schistosoma antibody, and the prevalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody were descriptively analyzed. Village-based spatial distribution characteristics of prevalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody were identified in Hunan Province in 2020, and the correlation between the revalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody was examined using Spearman correlation analysis.
RESULTS: The prevalence of advanced schistosomiasis was 0 to 2.72% and the seroprevalence of anti-Schistosoma antibody was 0 to 20.25% in 1 153 schistosomiasis-endemic villages in Hunan Province in 2020. Spatial clusters were identified in both the prevalence of advanced schistosomiasis (global Moran\'s I = 0.416, P < 0.01) and the seroprevalence of anti-Schistosoma antibody (global Moran\'s I = 0.711, P < 0.01) in Hunan Province. Local spatial autocorrelation analysis identified 98 schistosomiasis-endemic villages with high-high clusters of the prevalence of advanced schistosomiasis, 134 endemic villages with high-high clusters of the seroprevalence of anti-Schistosoma antibody and 36 endemic villages with high-high clusters of both the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody in Hunan Province. In addition, spearman correlation analysis showed a positive correlation between the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody (rs = 0.235, P < 0.05).
CONCLUSIONS: There were spatial clusters of the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody in Hunan Province in 2020, which were predominantly located in areas neighboring the Dongting Lake. These clusters should be given a high priority in the schistosomiasis control programs.
［摘要］ 目的 分析 2020 年湖南省人群晚期血吸虫病患病率和血清抗血吸虫抗体阳性率空间分布特征及其相关性, 为 湖南省晚期血吸虫病防治提供科学依据。方法 收集 2020 年湖南省血吸虫病疫情数据, 包括调查村常住人口数、晚期 血吸虫病病例数、血清学检查受检人数和血清抗血吸虫抗体阳性人数。以村为单位分析人群晚期血吸虫病患病率和血 清抗血吸虫抗体阳性率空间分布特征, 采用 Spearman 秩相关评估人群晚期血吸虫病患病率和血清抗血吸虫抗体阳性率 间的相关性。结果 2020 年, 湖南省 1 153 个血吸虫病流行村人群晚期血吸虫病患病率为 0 ~ 2.72%, 血清抗血吸虫抗体 阳性率为 0 ~ 20.25%。全局空间自相关分析发现, 湖南省晚期血吸虫病患病率 (全局 Moran’s I = 0.416, P < 0.01) 和血清 抗血吸虫抗体阳性率 (全局 Moran’s I = 0.711, P < 0.01) 均存在空间聚集性; 局部空间自相关分析发现, 湖南省晚期血吸 虫病患病率存在 98 个高-高聚集村、血清抗血吸虫抗体阳性率存在 134 个高-高聚集村、36 个村晚期血吸虫病患病率和血 清抗血吸虫抗体阳性率均存在高-高聚集。Spearman 秩相关分析显示, 居民晚期血吸虫病患病率与血清抗血吸虫抗体阳 性率呈正相关 (rs = 0.235, P < 0.05)。结论 2020 年湖南省居民晚期血吸虫病患病率与血清抗血吸虫抗体阳性率存在空 间聚集性, 主要分布于洞庭湖周边地区, 在现场防治工作中应重点关注聚集区域。.
METHODS: The epidemiological data of schistosomiasis in Hunan Province in 2020 were collected, including number of permanent residents in survey villages, number of advanced schistosomiasis patients, number of residents receiving serological tests and number of residents seropositive for anti-Schistosoma antibody, and the prevalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody were descriptively analyzed. Village-based spatial distribution characteristics of prevalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody were identified in Hunan Province in 2020, and the correlation between the revalence advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody was examined using Spearman correlation analysis.
RESULTS: The prevalence of advanced schistosomiasis was 0 to 2.72% and the seroprevalence of anti-Schistosoma antibody was 0 to 20.25% in 1 153 schistosomiasis-endemic villages in Hunan Province in 2020. Spatial clusters were identified in both the prevalence of advanced schistosomiasis (global Moran\'s I = 0.416, P < 0.01) and the seroprevalence of anti-Schistosoma antibody (global Moran\'s I = 0.711, P < 0.01) in Hunan Province. Local spatial autocorrelation analysis identified 98 schistosomiasis-endemic villages with high-high clusters of the prevalence of advanced schistosomiasis, 134 endemic villages with high-high clusters of the seroprevalence of anti-Schistosoma antibody and 36 endemic villages with high-high clusters of both the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody in Hunan Province. In addition, spearman correlation analysis showed a positive correlation between the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody (rs = 0.235, P < 0.05).
CONCLUSIONS: There were spatial clusters of the prevalence of advanced schistosomiasis and seroprevalence of anti-Schistosoma antibody in Hunan Province in 2020, which were predominantly located in areas neighboring the Dongting Lake. These clusters should be given a high priority in the schistosomiasis control programs.
［摘要］ 目的 分析 2020 年湖南省人群晚期血吸虫病患病率和血清抗血吸虫抗体阳性率空间分布特征及其相关性, 为 湖南省晚期血吸虫病防治提供科学依据。方法 收集 2020 年湖南省血吸虫病疫情数据, 包括调查村常住人口数、晚期 血吸虫病病例数、血清学检查受检人数和血清抗血吸虫抗体阳性人数。以村为单位分析人群晚期血吸虫病患病率和血 清抗血吸虫抗体阳性率空间分布特征, 采用 Spearman 秩相关评估人群晚期血吸虫病患病率和血清抗血吸虫抗体阳性率 间的相关性。结果 2020 年, 湖南省 1 153 个血吸虫病流行村人群晚期血吸虫病患病率为 0 ~ 2.72%, 血清抗血吸虫抗体 阳性率为 0 ~ 20.25%。全局空间自相关分析发现, 湖南省晚期血吸虫病患病率 (全局 Moran’s I = 0.416, P < 0.01) 和血清 抗血吸虫抗体阳性率 (全局 Moran’s I = 0.711, P < 0.01) 均存在空间聚集性; 局部空间自相关分析发现, 湖南省晚期血吸 虫病患病率存在 98 个高-高聚集村、血清抗血吸虫抗体阳性率存在 134 个高-高聚集村、36 个村晚期血吸虫病患病率和血 清抗血吸虫抗体阳性率均存在高-高聚集。Spearman 秩相关分析显示, 居民晚期血吸虫病患病率与血清抗血吸虫抗体阳 性率呈正相关 (rs = 0.235, P < 0.05)。结论 2020 年湖南省居民晚期血吸虫病患病率与血清抗血吸虫抗体阳性率存在空 间聚集性, 主要分布于洞庭湖周边地区, 在现场防治工作中应重点关注聚集区域。.
摘要：
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