METHODS: Full-mouth periodontal examination and radiographic analysis were used for evaluating periodontal condition based on the 2018 classification of periodontal disease. A dichotomous diagnosis of clinical periodontal condition was performed using the POC device. The relationships among periodontal condition and the concentration of MMP-8, tooth loss (TL), gingival index (GI), plaque index (PI), and alveolar bone loss (ABL) were assessed by the Spearman rank correlations (rs).
RESULTS: In all, 108 cases of non-periodontitis (NP) and 191 cases of periodontitis (P), including 38 cases of periodontitis stage I, 42 cases of periodontitis stage II, 99 cases of periodontitis stage III, and 11 cases of periodontitis stage IV, were enrolled in this study. Diagnostic accuracy in assessing periodontal condition with the POC device improved when it was used with participants aged ≥ 40 years. There were weak positive correlations between periodontal condition and MMP-8 and between periodontal condition and GI (rs2 = 0.1124 and rs2 = 0.0906, respectively), whereas a strong positive correlation between periodontal condition and alveolar bone loss (rs2 = 0.6877) was observed.
CONCLUSIONS: The POC device investigated in this study is a potential tool to distinguish between NP and P in individuals ≥ 40 years of age.
方法:根据2018年牙周病分类,采用全口牙周检查和影像学分析评估牙周状况。使用POC装置对临床牙周状况进行二分法诊断。牙周状况与MMP-8浓度,牙齿缺失(TL),牙龈指数(GI),菌斑指数(PI),和牙槽骨丢失(ABL)通过Spearman等级相关性(rs)进行评估。
结果:总而言之,非牙周炎(NP)108例,牙周炎(P)191例,其中Ⅰ期牙周炎38例,42例牙周炎II期,99例牙周炎Ⅲ期,11例牙周炎IV期,参加了这项研究。当与年龄≥40岁的参与者一起使用时,使用POC装置评估牙周状况的诊断准确性得到了提高。牙周状况与MMP-8之间以及牙周状况与GI之间存在弱正相关(分别为rs2=0.1124和rs2=0.0906)。而牙周状况与牙槽骨丢失之间存在很强的正相关(rs2=0.6877)。
结论:本研究中研究的POC装置是区分≥40岁个体中NP和P的潜在工具。