PDF(Pubmed)
Abstract：
UNASSIGNED: To analyze the relationship between leg skeletal muscle mass index (LSMI) and non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM) and the ability of LSMI to predict NAFLD.
UNASSIGNED: Two hundred patients with T2DM and NAFLD treated at Changzhou Second People\'s Hospital Affiliated with Nanjing Medical University and the National Metabolic Management Center from June 2022 to June 2023 were divided into four LSMI quartiles. The clinical information from the four patient groups was compared, and the relationship between type 2 diabetes and LSMI and NAFLD was examined. We used receiver operating characteristic curves to determine how well the LSMI predicts NAFLD in T2DM.
UNASSIGNED: The lowest quartile (Q1) had a higher prevalence of NAFLD than group Q4 (P < 0.05). LSMI was negatively associated with body mass index, LS, CAP, and other markers (P < 0.05). Receiver operating characteristic curve analysis LSMI predicted NAFLD with an ideal critical value of 0.64 and an area under the curve of 70.9%. The combined predictive value of the LSMI and the appendicular skeletal muscle mass index was more significant.
UNASSIGNED: Reduced LSMI is associated with NAFLD.
UNASSIGNED: Two hundred patients with T2DM and NAFLD treated at Changzhou Second People\'s Hospital Affiliated with Nanjing Medical University and the National Metabolic Management Center from June 2022 to June 2023 were divided into four LSMI quartiles. The clinical information from the four patient groups was compared, and the relationship between type 2 diabetes and LSMI and NAFLD was examined. We used receiver operating characteristic curves to determine how well the LSMI predicts NAFLD in T2DM.
UNASSIGNED: The lowest quartile (Q1) had a higher prevalence of NAFLD than group Q4 (P < 0.05). LSMI was negatively associated with body mass index, LS, CAP, and other markers (P < 0.05). Receiver operating characteristic curve analysis LSMI predicted NAFLD with an ideal critical value of 0.64 and an area under the curve of 70.9%. The combined predictive value of the LSMI and the appendicular skeletal muscle mass index was more significant.
UNASSIGNED: Reduced LSMI is associated with NAFLD.
摘要：
■分析2型糖尿病(T2DM)患者腿部骨骼肌质量指数(LSMI)与非酒精性脂肪性肝病(NAFLD)的关系及LSMI对NAFLD的预测能力。
■将2022年6月至2023年6月在南京医科大学附属常州第二人民医院和国家代谢管理中心治疗的两百名T2DM和NAFLD患者分为四个LSMI四分位数。比较四组患者的临床信息，并探讨2型糖尿病与LSMI和NAFLD的关系。我们使用接收器工作特征曲线来确定LSMI对T2DM中NAFLD的预测程度。
■最低四分位数（Q1）组的NAFLD患病率高于Q4组（P<0.05）。LSMI与体重指数呈负相关，LS,CAP,和其他标记物(P<0.05)。接收器工作特征曲线分析LSMI预测NAFLD的理想临界值为0.64，曲线下面积为70.9％。LSMI和阑尾骨骼肌质量指数的联合预测价值更显著。
■降低的LSMI与NAFLD相关。
■将2022年6月至2023年6月在南京医科大学附属常州第二人民医院和国家代谢管理中心治疗的两百名T2DM和NAFLD患者分为四个LSMI四分位数。比较四组患者的临床信息，并探讨2型糖尿病与LSMI和NAFLD的关系。我们使用接收器工作特征曲线来确定LSMI对T2DM中NAFLD的预测程度。
■最低四分位数（Q1）组的NAFLD患病率高于Q4组（P<0.05）。LSMI与体重指数呈负相关，LS,CAP,和其他标记物(P<0.05)。接收器工作特征曲线分析LSMI预测NAFLD的理想临界值为0.64，曲线下面积为70.9％。LSMI和阑尾骨骼肌质量指数的联合预测价值更显著。
■降低的LSMI与NAFLD相关。
