PDF(Pubmed)
Abstract：
In this report, we present a case study of a rare human bacterium, Corynebacterium bovis, which caused an infection in a patient who had undergone autologous fat-based breast augmentation using cryopreserved fat. This infection occurred during a secondary fat grafting procedure. To identify the bacteria causing the infection, we used high-throughput DNA sequencing technology since this bacterium is seldomly reported in human infections. The patient was successfully treated with intravenous imipenem. We also discuss potential factors that may have contributed to this unusual bacterial infection and propose that DNA sequencing can be a useful tool in cases where standard culture techniques fail to identify the causative agent. Additionally, we highlight the importance of further research on the cryopreservation of fat. In summary, this case highlights the possibility of rare bacterial infections occurring after fat grafting procedures and emphasizes the importance of identifying the causative agent through advanced techniques such as DNA sequencing. Further research is needed to improve our understanding of the risks associated with cryopreservation of fat and to identify ways to prevent these types of infections in the future.
摘要：
在这份报告中,我们提供了一个罕见的人类细菌的案例研究，牛棒状杆菌,导致一名患者感染，该患者使用冷冻脂肪进行了自体脂肪隆胸手术。这种感染发生在二次脂肪移植过程中。为了确定引起感染的细菌，我们使用了高通量DNA测序技术，因为这种细菌在人类感染中很少报道。患者经静脉注射亚胺培南成功治疗。我们还讨论了可能导致这种异常细菌感染的潜在因素，并提出在标准培养技术无法识别病原体的情况下，DNA测序可能是有用的工具。此外,我们强调了进一步研究脂肪冷冻保存的重要性。总之,该病例强调了脂肪移植手术后发生罕见细菌感染的可能性,并强调了通过DNA测序等先进技术鉴定病原体的重要性.需要进一步的研究来提高我们对脂肪冷冻保存相关风险的理解，并确定未来预防这些类型感染的方法。
