关键词: allergen immunotherapy (AIT) biologicals biomarkers component-resolved diagnosis (CRD) randomized controlled trial (RCT) real-world evidence (RWE)

来  源:   DOI:10.5414/ALX02379E   PDF(Pubmed)

Abstract:
Although used for over 100 years, allergen immunotherapy (AIT) is still an indispensable tool in modern allergy managemen20t due to its potential to cure allergic diseases. Its current rapid development through the application of personalized and precision medicine approaches is strongly supported by advances in mHealth, component-resolved diagnosis (CRD)-based diagnostics, validation of novel biomarkers, advanced data management, and development of novel preparations. This review summarizes the key advances in the field and shows the perspectives for further development of next-generation AIT treatments.
摘要:
虽然已经使用了100多年,过敏原免疫疗法(AIT)由于其治愈过敏性疾病的潜力,仍然是现代过敏管理中不可或缺的工具。通过应用个性化和精准医学方法,其当前的快速发展得到了mHealth进步的大力支持,基于组件解析诊断(CRD)的诊断,新型生物标志物的验证,先进的数据管理,和新型制剂的开发。这篇综述总结了该领域的关键进展,并展示了进一步开发下一代AIT治疗的前景。
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