Abstract:
Herein, we describe a case of acute rhabdomyolysis in a man in his early 50s undergoing haemodialysis and receiving the antiviral drug, telbivudine, for chronic hepatitis B virus (HBV) infection. Following diagnosis by electromyography (EMG), magnetic resonance image (MRI) scans and laboratory data (i.e., elevated serum creatinine kinase (CK) and myoglobin) telbivudine was discontinued and the patient was treated with methylprednisolone. While his CK and myoglobin levels decreased rapidly, his muscle weakness and pain improved slowly. Learning points include: patients undergoing haemodialysis and concomitantly receiving antiviral treatment for HBV, should have their serum levels of CK and myoglobin monitored regularly; treatment with corticosteroids maybe required; relief from rhabdomyolysis-induced muscle weakness and pain may be slow due to nerve fibre damage.
摘要:
在这里,我们描述了一个50岁出头的男性急性横纹肌溶解症病例,接受血液透析和抗病毒药物治疗,替比夫定,用于慢性乙型肝炎病毒(HBV)感染。在通过肌电图(EMG)诊断后,磁共振图像(MRI)扫描和实验室数据(即,血清肌酐激酶(CK)和肌红蛋白)升高停用替比夫定,患者接受甲基强的松龙治疗.虽然他的CK和肌红蛋白水平迅速下降,他的肌肉无力和疼痛慢慢改善。学习点包括:患者接受血液透析和同时接受抗病毒治疗的HBV,应定期监测血清CK和肌红蛋白水平;可能需要使用皮质类固醇治疗;由于神经纤维损伤,横纹肌溶解引起的肌肉无力和疼痛的缓解可能会缓慢。