PDF(Pubmed)
Abstract：
Eosinophilic esophagitis (EoE) is an immune-mediated disease that manifests with dysphagia and is characterized by the predominantly eosinophilic infiltration of the esophageal mucosa. Several instruments have been developed to assess the symptoms of EoE: the Daily Symptom Questionnaire (DSQ), EoE Activity Index (EEsAI), Pediatric EoE Symptom Severity (PEESSv2), etc. The use of the EREFS is a gold standard for endoscopic diagnosis. The EoE histologic scoring system (EoEHSS) was elaborated for the assessment of histological features in EoE. However, the remission criteria are not clearly defined and vary greatly in different studies. Gastroenterologists establish the severity of EoE mainly based on endoscopic findings. At the same time, EoE requires a multidisciplinary approach. The recently developed Index of Severity of Eosinophilic Esophagitis (I-SEE) that is built on symptoms, endoscopic findings, and histological features is promising.
摘要：
嗜酸性粒细胞性食管炎（EoE）是一种免疫介导的疾病，表现为吞咽困难，其特征是食管粘膜的嗜酸性粒细胞浸润。已经开发了几种工具来评估EoE的症状：每日症状问卷（DSQ），EoE活动指数(EEsAI)，儿科EoE症状严重程度（PEESSv2），等。EREFS的使用是内窥镜诊断的金标准。EoE组织学评分系统（EoEHSS）用于评估EoE的组织学特征。然而,缓解标准没有明确定义，在不同的研究中差异很大。胃肠病学家主要根据内镜检查结果确定EoE的严重程度。同时,EoE需要多学科方法。最近开发的嗜酸性粒细胞性食管炎严重程度指数（I-SEE）建立在症状上，内镜检查结果,和组织学特征是有希望的。
