PDF(Pubmed)
Abstract：
The significance of sample grinding is frequently disregarded during the development of analytical methods, which are often validated with spiked samples that may not accurately reflect incurred residues. This study investigated the particle size of ground beans as a key factor in optimizing extraction efficiency in order to develop a simple quick, easy, cheap, effective, rugged, and safe (QuEChERS)-based modified method for identifying 380 pesticides in beans using liquid chromatography-tandem mass spectrometry. The efficacy of pesticide extraction was found to be significantly affected by particle size. With small particle sizes (>40 mesh), no supernatant was recovered after QuEChERS partitioning. Therefore, a simple modification was performed before partitioning. The modified method was validated for selective extraction of pesticides, limits of quantification, linearity, accuracy, and precision. This method is simple to implement and, therefore, useful for the analysis of pesticide residues in beans.
摘要：
在分析方法的开发过程中，经常忽略样品研磨的重要性，通常使用加标样品进行验证，这些样品可能无法准确反映发生的残留物。这项研究调查了研磨豆的粒度作为优化提取效率的关键因素，以开发一种简单快速，easy,便宜,有效,崎岖,基于安全（QuEChERS）的改良方法，使用液相色谱-串联质谱法鉴定豆类中的380种农药。发现农药提取的功效受粒径的显着影响。小粒径（>40目），QuEChERS分离后没有回收上清液。因此,在分区之前进行了简单的修改。改进后的方法已用于农药的选择性提取，量化的极限，线性度准确度,和精度。该方法实现简单,因此,用于分析豆类中的农药残留。
