Abstract：
BACKGROUND: Keeping children nil by mouth until return of bowel function after intestinal anastomosis surgery is said to reduce complications. Fasting may extend up to five days, risking malnourishment and usage of parenteral nutrition. This study aims to establish the efficacy and safety of early enteral nutrition in children undergoing intestinal stoma closure.
METHODS: A retrospective cohort study of children aged three months to 16 years who underwent an intestinal stoma closure between 1/1/2019 and 31/12/2021 at two tertiary paediatric hospitals was undertaken. Children fed clear fluids within 24 h (EEN) were compared to those commencing feeds later (LEN). The primary outcome was length of post-operative stay (LOS) and secondary outcomes included: time to feeds; time to stool; and complications.
RESULTS: Of the 129 children that underwent a stoma closure, 69 met inclusion criteria: 35 (51 %) in the LEN group and 34 (49 %) in the EEN group. Children in the EEN group had a significantly shorter LOS (92.6 h vs 121.7 h, p = 0.0045). Early feeding was also associated with a significantly decreased time to free fluids (p < 0.001) and full enteral intake (p = 0.007). There was no significant intergroup difference in complications.
CONCLUSIONS: Commencing feeding within 24 h of stoma closure is efficacious and safe, with clear reductions in LOS, time to full feeds and time to stool, and no increase in complications. Further research is required to extrapolate these findings to other populations.
METHODS: III.
METHODS: A retrospective cohort study of children aged three months to 16 years who underwent an intestinal stoma closure between 1/1/2019 and 31/12/2021 at two tertiary paediatric hospitals was undertaken. Children fed clear fluids within 24 h (EEN) were compared to those commencing feeds later (LEN). The primary outcome was length of post-operative stay (LOS) and secondary outcomes included: time to feeds; time to stool; and complications.
RESULTS: Of the 129 children that underwent a stoma closure, 69 met inclusion criteria: 35 (51 %) in the LEN group and 34 (49 %) in the EEN group. Children in the EEN group had a significantly shorter LOS (92.6 h vs 121.7 h, p = 0.0045). Early feeding was also associated with a significantly decreased time to free fluids (p < 0.001) and full enteral intake (p = 0.007). There was no significant intergroup difference in complications.
CONCLUSIONS: Commencing feeding within 24 h of stoma closure is efficacious and safe, with clear reductions in LOS, time to full feeds and time to stool, and no increase in complications. Further research is required to extrapolate these findings to other populations.
METHODS: III.
摘要：
背景：据说在肠吻合术后将儿童口服至肠道功能恢复可减少并发症。禁食可能会持续五天，有营养不良和使用肠外营养的风险。本研究旨在建立早期肠内营养在肠造口关闭患儿中的有效性和安全性。
方法：对在2019年1月1日至2021年31月12日期间在两家三级儿科医院接受肠造口关闭的3个月至16岁儿童进行了回顾性队列研究。将24小时内（EEN）喂食清澈液体的儿童与以后开始喂食的儿童（LEN）进行比较。主要结局是术后住院时间（LOS），次要结局包括：进食时间；大便时间；和并发症。
结果：在129名接受造口闭合的儿童中，69人符合纳入标准：LEN组35人（51%），EEN组34人（49%）。EEN组的儿童LOS明显较短（92.6hvs121.7h，p=0.0045)。早期进食还与获得游离液体的时间显着减少（p<0.001）和完全肠内摄入（p=0.007）有关。并发症无显著组间差异。
结论：在造口闭合后24小时内开始喂食是有效且安全的，随着LOS的明显减少，吃饱的时间和大便的时间，没有增加并发症。需要进一步的研究将这些发现推断到其他人群。
方法：III.
方法：对在2019年1月1日至2021年31月12日期间在两家三级儿科医院接受肠造口关闭的3个月至16岁儿童进行了回顾性队列研究。将24小时内（EEN）喂食清澈液体的儿童与以后开始喂食的儿童（LEN）进行比较。主要结局是术后住院时间（LOS），次要结局包括：进食时间；大便时间；和并发症。
结果：在129名接受造口闭合的儿童中，69人符合纳入标准：LEN组35人（51%），EEN组34人（49%）。EEN组的儿童LOS明显较短（92.6hvs121.7h，p=0.0045)。早期进食还与获得游离液体的时间显着减少（p<0.001）和完全肠内摄入（p=0.007）有关。并发症无显著组间差异。
结论：在造口闭合后24小时内开始喂食是有效且安全的，随着LOS的明显减少，吃饱的时间和大便的时间，没有增加并发症。需要进一步的研究将这些发现推断到其他人群。
方法：III.
