PDF(Pubmed)
Abstract：
Salmonellosis is a disease transmitted by contaminated food and is one of the leading causes of infections worldwide, making the early detection of Salmonella of crucial importance for public health. However, current detection methods are laborious and time-consuming, thus impacting the entire food supply chain and leading to production losses and economic sanctions. To mitigate these issues, a number of different biosensors have been developed, including lateral flow assays (LFAs), which have emerged as valuable tools in pathogen detection due to their portability, ease of use, time efficiency, and cost effectiveness. The performance of LFAs has been considerably enhanced by the development of new nanomaterials over the years. In this review, we address the principles and formats of the assay and discuss future prospects and challenges with an emphasis on LFAs developed for the detection of different Salmonella serovars in food.
摘要：
沙门氏菌病是由受污染的食物传播的疾病，是全球感染的主要原因之一，使沙门氏菌的早期检测对公共卫生至关重要。然而,目前的检测方法既费力又费时，从而影响整个食品供应链，导致生产损失和经济制裁。为了缓解这些问题，已经开发了许多不同的生物传感器，包括侧流测定(LFA)，由于它们的便携性，它们已经成为病原体检测中的有价值的工具，易用性,时间效率,和成本效益。多年来，新型纳米材料的开发大大提高了LFA的性能。在这次审查中,我们讨论了该测定的原理和格式，并讨论了未来的前景和挑战，重点是为检测食品中不同沙门氏菌血清型而开发的LFA。
