PDF(Pubmed)
Abstract：
This pilot study analyzed correlations between tongue electrical impedance myography (EIM), standard tongue electromyography (EMG), and tongue functional measures in N = 4 long-term oropharyngeal cancer (OPC) survivors.
Patients were screened for a supportive care trial (NCT04151082). Hypoglossal nerve function was evaluated with genioglossus needle EMG, functional measures with the Iowa oral performance instrument (IOPI), and multi-frequency tissue composition with tongue EIM.
Tongue EIM conductivity was higher for patients with EMG-confirmed cranial nerve XII neuropathy than those without (p = 0.005) and in patients with mild versus normal EMG reinnervation ratings (16 kHz EIM: p = 0.051). Tongue EIM correlated with IOPI strength measurements (e.g., anterior maximum isometric lingual strength: r2 = 0.62, p = 0.020).
Tongue EIM measures related to tongue strength and the presence of XII neuropathy. Noninvasive tongue EIM may be a convenient adjunctive biomarker to assess tongue health in OPC survivors.
Patients were screened for a supportive care trial (NCT04151082). Hypoglossal nerve function was evaluated with genioglossus needle EMG, functional measures with the Iowa oral performance instrument (IOPI), and multi-frequency tissue composition with tongue EIM.
Tongue EIM conductivity was higher for patients with EMG-confirmed cranial nerve XII neuropathy than those without (p = 0.005) and in patients with mild versus normal EMG reinnervation ratings (16 kHz EIM: p = 0.051). Tongue EIM correlated with IOPI strength measurements (e.g., anterior maximum isometric lingual strength: r2 = 0.62, p = 0.020).
Tongue EIM measures related to tongue strength and the presence of XII neuropathy. Noninvasive tongue EIM may be a convenient adjunctive biomarker to assess tongue health in OPC survivors.
摘要：
背景：这项初步研究分析了舌头电阻抗肌电图（EIM）之间的相关性，标准舌肌电图（EMG），和舌功能测量在N=4长期口咽癌（OPC）幸存者。
方法：筛选患者进行支持治疗试验（NCT04151082）。舌舌下神经功能采用舌舌肌肌电图,用爱荷华州口腔性能仪器(IOPI)进行功能测量，和多频率组织成分与舌EIM。
结果：经EMG证实的颅神经XII神经病患者的舌骨EIM电导率高于无（p=0.005）和轻度与正常EMG神经支配等级（16kHzEIM：p=0.051）的患者。舌头EIM与IOPI强度测量相关(例如，前最大等距舌强度：r2=0.62，p=0.020）。
结论：舌EIM测量与舌强度和XII神经病的存在有关。非侵入性舌头EIM可能是评估OPC幸存者舌头健康的方便的辅助生物标志物。
方法：筛选患者进行支持治疗试验（NCT04151082）。舌舌下神经功能采用舌舌肌肌电图,用爱荷华州口腔性能仪器(IOPI)进行功能测量，和多频率组织成分与舌EIM。
结果：经EMG证实的颅神经XII神经病患者的舌骨EIM电导率高于无（p=0.005）和轻度与正常EMG神经支配等级（16kHzEIM：p=0.051）的患者。舌头EIM与IOPI强度测量相关(例如，前最大等距舌强度：r2=0.62，p=0.020）。
结论：舌EIM测量与舌强度和XII神经病的存在有关。非侵入性舌头EIM可能是评估OPC幸存者舌头健康的方便的辅助生物标志物。
