PDF(Pubmed)
Abstract：
Psammocarcinoma (PsC) represents a rare form of low-grade serous tumor of the ovary or peritoneum. Although ovarian cancer generally has a poor prognosis in its late stages, PsC seems to have a more indolent course. We present a patient with a history of unspecific abdominal pain for more than a year, with sudden acute onset of severe inguinal pain. On admission to the hospital, a computed tomography (CT) revealed a pelvic mass of suspected ovarian origin. Radical surgery was attempted but not achieved due to widespread tumor growth. Histopathological evaluation revealed estrogen receptor-positive stage III PsC. Tamoxifen treatment was thus initiated, still maintaining stable disease 10 years later. The patient has undergone extensive radiological work-up, including CT, chest X-ray, 18F-fluoro-deoxy-glucose positron emission tomography (PET)/CT, 99mTc- hydroxymethylene diphosphonate (HDP) bone scintigraphy, 18F-fluoro-thymidine (FLT) PET/CT, Tc-99m depreotide scintigraphy and magnetic resonance imaging. In conclusion, we demonstrate that PsC has characteristic radiological features and different imaging modalities can be suitable in different clinical situations. In contrast to most other ovarian cancers, PsC does not always warrant adjuvant chemotherapy, even in advanced stages. This emphasizes the need for a deeper knowledge of the biological behavior of this rare tumor, to select the optimal treatment strategy.
摘要：
喉癌（PsC）代表一种罕见的卵巢或腹膜低度浆液性肿瘤。尽管卵巢癌在晚期通常预后较差，PsC似乎有一个更懒惰的过程。我们介绍一名患者有一年以上的非特异性腹痛史，伴有突然急性发作的严重腹股沟疼痛。入院后，计算机断层扫描（CT）显示可疑卵巢起源的盆腔肿块。尝试了根治性手术，但由于肿瘤广泛生长而未实现。组织病理学评估显示雌激素受体阳性III期PsC。因此开始了他莫昔芬治疗，10年后仍保持病情稳定。病人接受了广泛的放射检查,包括CT,胸部X光,18F-氟脱氧葡萄糖正电子发射断层扫描(PET)/CT,99mTc-羟基亚甲基二膦酸盐（HDP）骨闪烁显像，18F-氟代胸苷(FLT)PET/CT,Tc-99mdepreotide闪烁显像和磁共振成像。总之,我们证明PsC具有特征性的放射学特征，不同的影像学检查方式可适用于不同的临床情况。与大多数其他卵巢癌相比，PsC并不总是需要辅助化疗，即使在高级阶段。这强调需要对这种罕见肿瘤的生物学行为有更深入的了解，选择最优的治疗策略。
