PDF(Pubmed)
Abstract：
BACKGROUND: Thyroid cancer is not commonly observed in patients with Graves\' disease (GD). The presence of thyroid nodules in GD is not uncommon. However, a link between these two entities has been reported. Herein, we report the case of a patient with GD and thyroid cancer in Saudi Arabia, which has not been reported previously in our region.
METHODS: A 26-year-old male patient with GD, receiving carbimazole for 2 years, presented to our hospital. His hyperthyroidism was controlled clinically and biochemically. On clinical examination, he was found to have a left-sided thyroid nodule. Ultrasound revealed a 2.6 cm hypoechoic nodule with high vascularity. He was then referred for fine needle aspiration which showed that the nodule was highly suspicious for malignancy. The patient underwent total thyroidectomy and was diagnosed with multifocal classical micropapillary thyroid cancer. Post thyroidectomy he received radioactive iodine ablation along with levothyroxine replacement therapy.
CONCLUSIONS: Careful preoperative assessment and thyroid gland ultrasound might assist in screening and diagnosing thyroid cancer in patients with GD.
METHODS: A 26-year-old male patient with GD, receiving carbimazole for 2 years, presented to our hospital. His hyperthyroidism was controlled clinically and biochemically. On clinical examination, he was found to have a left-sided thyroid nodule. Ultrasound revealed a 2.6 cm hypoechoic nodule with high vascularity. He was then referred for fine needle aspiration which showed that the nodule was highly suspicious for malignancy. The patient underwent total thyroidectomy and was diagnosed with multifocal classical micropapillary thyroid cancer. Post thyroidectomy he received radioactive iodine ablation along with levothyroxine replacement therapy.
CONCLUSIONS: Careful preoperative assessment and thyroid gland ultrasound might assist in screening and diagnosing thyroid cancer in patients with GD.
摘要：
背景：在患有Graves病（GD）的患者中，甲状腺癌并不常见。GD中甲状腺结节的存在并不少见。然而,据报道，这两个实体之间存在联系。在这里，我们报道了沙特阿拉伯的一名患有GD和甲状腺癌的患者，这在我们地区以前没有报道过。
方法：一名26岁男性GD患者，接受卡比马唑治疗2年，送到我们医院。他的甲状腺功能亢进在临床和生化上得到控制。在临床检查中，他被发现患有左侧甲状腺结节。超声显示2.6cm低回声结节，血管分布较高。然后，他被转诊进行细针穿刺，这表明结节高度可疑为恶性肿瘤。该患者接受了甲状腺全切除术，并被诊断为多灶性经典微乳头状甲状腺癌。甲状腺切除术后，他接受了放射性碘消融和左甲状腺素替代疗法。
结论：术前仔细评估和甲状腺超声检查可能有助于GD患者甲状腺癌的筛查和诊断。
方法：一名26岁男性GD患者，接受卡比马唑治疗2年，送到我们医院。他的甲状腺功能亢进在临床和生化上得到控制。在临床检查中，他被发现患有左侧甲状腺结节。超声显示2.6cm低回声结节，血管分布较高。然后，他被转诊进行细针穿刺，这表明结节高度可疑为恶性肿瘤。该患者接受了甲状腺全切除术，并被诊断为多灶性经典微乳头状甲状腺癌。甲状腺切除术后，他接受了放射性碘消融和左甲状腺素替代疗法。
结论：术前仔细评估和甲状腺超声检查可能有助于GD患者甲状腺癌的筛查和诊断。
