关键词: atypical rash atypical syphilis moth-eaten pattern secondary syphilis syphilis

来  源:   DOI:10.7759/cureus.49181   PDF(Pubmed)

Abstract:
Syphilis is a re-emerging disease, and an increasing number of cases are being reported in Italy and worldwide. In this report, we present a case of a male patient with secondary syphilis characterized by the heterogenicity of the lesions: hyperkeratosis, psoriasiform-like lesions, papules, macules, and patchy alopecia on the scalp. The patient had applied several topical antimicrobials and steroid medicaments and taken oral acyclovir, which yielded no relief, for a previous wrong diagnosis. At the time of his presentation to our clinic, syphilis was suspected and confirmed by serology. The administration of a single intramuscular dose of penicillin led to a full recovery in three weeks. Screening for HIV and other sexually transmitted infections returned negative. Clinicians should maintain a high index of suspicion for syphilis when encountering sexually active patients with atypical skin manifestations.
摘要:
梅毒是一种重新出现的疾病,越来越多的病例被报告在意大利和世界各地。在这份报告中,我们介绍了一例男性二期梅毒患者,其特征是病变的异质性:角化过度,银屑病样病变,丘疹,斑斑,头皮上有斑片状脱发。患者应用了几种局部抗菌药物和类固醇药物,并口服了阿昔洛韦,没有得到任何缓解,以前的错误诊断。在他向我们诊所介绍的时候,梅毒被怀疑并通过血清学证实。单次肌内注射青霉素可在三周内完全恢复。艾滋病毒和其他性传播感染的筛查结果为阴性。当遇到具有非典型皮肤表现的性活跃患者时,临床医生应保持对梅毒的高度怀疑。
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