PDF(Pubmed)
Abstract：
UNASSIGNED: We aimed to provide a timely, comprehensive, and reliable assessment of the burden of iron deficiency (ID) in children between 1990 and 2019 at the global, regional, and national levels to inform policymakers in developing locally appropriate health policies.
UNASSIGNED: Data related to ID among children younger than 15 years old were analyzed by sex, age, year, socio-demographic index (SDI), and location according to the Global Burden of Disease Study 2019 (GBD 2019). Age-standardized rates were used to compare the burden between different regions and countries. Furthermore, the Joinpoint regression model was used to assess temporal trends from 1990 to 2019.
UNASSIGNED: In 2019, the number of prevalent cases and disability-adjusted life years (DALYs) for ID in children were 391,491,699 and 13,620,231, respectively. The global age-standardized prevalence and DALY rates for childhood ID in 2019 were 20,146.35 (95% confidence interval: 19,407.85 to 20,888.54) and 698.90 (466.54 to 1015.31) per 100,000, respectively. Over the past 30 years, the global prevalence of ID among children has been highest in low-SDI regions, particularly in Western Sub-Saharan Africa, South Asia, and Eastern Sub-Saharan Africa. Since 1990, the prevalence and DALY of ID in children have been declining in most geographic regions. Nationally, Ecuador, China, and Chile have shown the most significant decreases in prevalence. The greatest decline in age-standardized DALY rate was observed in Ecuador, while Burkina Faso experienced the highest increase. Bhutan had the highest prevalence and DALY rates in 2019. On the age level, the prevalence was relatively higher among the <5 years age group. At the gender dimension, the prevalence of ID in children overall was more pronounced in girls than in boys, as was the case for DALY.
UNASSIGNED: Although the burden of ID in children has been declining, this disease remains a major public health problem, especially in countries with low SDI. Children younger than 5 years of age are an important group for whom targeted measures are needed to reduce the burden of ID.
UNASSIGNED: Data related to ID among children younger than 15 years old were analyzed by sex, age, year, socio-demographic index (SDI), and location according to the Global Burden of Disease Study 2019 (GBD 2019). Age-standardized rates were used to compare the burden between different regions and countries. Furthermore, the Joinpoint regression model was used to assess temporal trends from 1990 to 2019.
UNASSIGNED: In 2019, the number of prevalent cases and disability-adjusted life years (DALYs) for ID in children were 391,491,699 and 13,620,231, respectively. The global age-standardized prevalence and DALY rates for childhood ID in 2019 were 20,146.35 (95% confidence interval: 19,407.85 to 20,888.54) and 698.90 (466.54 to 1015.31) per 100,000, respectively. Over the past 30 years, the global prevalence of ID among children has been highest in low-SDI regions, particularly in Western Sub-Saharan Africa, South Asia, and Eastern Sub-Saharan Africa. Since 1990, the prevalence and DALY of ID in children have been declining in most geographic regions. Nationally, Ecuador, China, and Chile have shown the most significant decreases in prevalence. The greatest decline in age-standardized DALY rate was observed in Ecuador, while Burkina Faso experienced the highest increase. Bhutan had the highest prevalence and DALY rates in 2019. On the age level, the prevalence was relatively higher among the <5 years age group. At the gender dimension, the prevalence of ID in children overall was more pronounced in girls than in boys, as was the case for DALY.
UNASSIGNED: Although the burden of ID in children has been declining, this disease remains a major public health problem, especially in countries with low SDI. Children younger than 5 years of age are an important group for whom targeted measures are needed to reduce the burden of ID.
摘要：
■我们的目标是及时提供，全面,以及对1990年至2019年全球儿童缺铁（ID）负担的可靠评估，区域,为决策者制定适合当地的卫生政策提供信息。
■按性别分析了15岁以下儿童与ID相关的数据，年龄,Year,社会人口指数（SDI），和位置根据2019年全球疾病负担研究（GBD2019）。使用年龄标准化的比率来比较不同地区和国家之间的负担。此外，使用Joinpoint回归模型评估1990年至2019年的时间趋势。
■2019年，儿童ID的流行病例数和残疾调整寿命年（DALYs）分别为391,491,699和13,620,231。2019年全球儿童ID的年龄标准化患病率和DALY率分别为每10万人20,146.35（95％置信区间：19,407.85至20,888.54）和698.90（466.54至1015.31）。在过去的30年里,在SDI低的地区，全球儿童的ID患病率最高，特别是在撒哈拉以南非洲西部，南亚,和撒哈拉以南非洲东部。自1990年以来，儿童ID的患病率和DALY在大多数地理区域都在下降。在全国范围内,厄瓜多尔,中国,和智利的患病率下降幅度最大。在厄瓜多尔观察到年龄标准化的DALY率下降幅度最大，布基纳法索的增幅最高。不丹在2019年的患病率和DALY率最高。在年龄层面,<5岁年龄组的患病率相对较高。在性别层面，儿童的ID患病率总体上在女孩比男孩更明显，就像DALY的情况一样。
■尽管儿童身份负担一直在下降，这种疾病仍然是一个主要的公共卫生问题，特别是在SDI较低的国家。5岁以下的儿童是一个重要群体，需要采取有针对性的措施来减轻身份证负担。
■按性别分析了15岁以下儿童与ID相关的数据，年龄,Year,社会人口指数（SDI），和位置根据2019年全球疾病负担研究（GBD2019）。使用年龄标准化的比率来比较不同地区和国家之间的负担。此外，使用Joinpoint回归模型评估1990年至2019年的时间趋势。
■2019年，儿童ID的流行病例数和残疾调整寿命年（DALYs）分别为391,491,699和13,620,231。2019年全球儿童ID的年龄标准化患病率和DALY率分别为每10万人20,146.35（95％置信区间：19,407.85至20,888.54）和698.90（466.54至1015.31）。在过去的30年里,在SDI低的地区，全球儿童的ID患病率最高，特别是在撒哈拉以南非洲西部，南亚,和撒哈拉以南非洲东部。自1990年以来，儿童ID的患病率和DALY在大多数地理区域都在下降。在全国范围内,厄瓜多尔,中国,和智利的患病率下降幅度最大。在厄瓜多尔观察到年龄标准化的DALY率下降幅度最大，布基纳法索的增幅最高。不丹在2019年的患病率和DALY率最高。在年龄层面,<5岁年龄组的患病率相对较高。在性别层面，儿童的ID患病率总体上在女孩比男孩更明显，就像DALY的情况一样。
■尽管儿童身份负担一直在下降，这种疾病仍然是一个主要的公共卫生问题，特别是在SDI较低的国家。5岁以下的儿童是一个重要群体，需要采取有针对性的措施来减轻身份证负担。
