Abstract：
OBJECTIVE: To determine possible effects of unilateral alveolar cleft closure on internal nasal volume and external nasolabial surface.
METHODS: Retrospective, single-arm, cohort study.
METHODS: Institutional, tertiary care.
METHODS: Patients with complete unilateral cleft lip, alveolus, and palate (CUCLAP), who underwent closure of the alveolar cleft with autologous bone graft (ABG) at the age of 9-11 years, with cone beam computed tomography (CBCT) and/or three-dimensional (3D) stereophotogrammetry images taken before and one year after the ABG procedure.
METHODS: ABG-pocedure in patients with CUCLAP.
METHODS: The influence of ABG on the internal and external nasal morphology.
RESULTS: A total of 28 patients (21M/7F, 14R/14L) were divided into internal (CBCT) and external (3D-stereophotogrammetry) measurement subgroups. The external nasolabial surface showed a significant decrease of the angle alar curvature right-subnasale-alar curvature left (-1.99°; P = .02; 95% CI -2.61, -0.36) and an increase of the linear measurement between these points (+1.01 mm; P = .03; 95% CI: 0.11, 1.91). No significant differences were found when comparing the distance maps of the affected side with the non-affected side (P = .50, 95% CI: -0.20, 0.29).
CONCLUSIONS: Closure of the alveolar cleft in CUCLAP patients with ABG did not affect the internal nasal volume, but significantly affected the external nasal surface. The procedure resulted in the nose becoming wider because both alar curvatures moved caudally and laterally relative to the subnasale.
METHODS: Retrospective, single-arm, cohort study.
METHODS: Institutional, tertiary care.
METHODS: Patients with complete unilateral cleft lip, alveolus, and palate (CUCLAP), who underwent closure of the alveolar cleft with autologous bone graft (ABG) at the age of 9-11 years, with cone beam computed tomography (CBCT) and/or three-dimensional (3D) stereophotogrammetry images taken before and one year after the ABG procedure.
METHODS: ABG-pocedure in patients with CUCLAP.
METHODS: The influence of ABG on the internal and external nasal morphology.
RESULTS: A total of 28 patients (21M/7F, 14R/14L) were divided into internal (CBCT) and external (3D-stereophotogrammetry) measurement subgroups. The external nasolabial surface showed a significant decrease of the angle alar curvature right-subnasale-alar curvature left (-1.99°; P = .02; 95% CI -2.61, -0.36) and an increase of the linear measurement between these points (+1.01 mm; P = .03; 95% CI: 0.11, 1.91). No significant differences were found when comparing the distance maps of the affected side with the non-affected side (P = .50, 95% CI: -0.20, 0.29).
CONCLUSIONS: Closure of the alveolar cleft in CUCLAP patients with ABG did not affect the internal nasal volume, but significantly affected the external nasal surface. The procedure resulted in the nose becoming wider because both alar curvatures moved caudally and laterally relative to the subnasale.
摘要：
目的：确定单侧肺泡裂隙闭合对鼻内容积和鼻唇沟表面的可能影响。
方法：回顾性，单臂,队列研究。
方法：机构，三级护理。
方法：单侧完全性唇裂患者，肺泡,和腭（CUCLAP），在9-11岁时接受自体骨移植（ABG）封闭牙槽突裂，使用ABG手术之前和之后一年拍摄的锥形束计算机断层扫描（CBCT）和/或三维（3D）立体摄影测量图像。
方法：CUCLAP患者的ABG治疗。
方法：ABG对鼻内外形态的影响。
结果：共有28例患者（21M/7F，14R/14L）分为内部（CBCT）和外部（3D立体摄影测量）测量亚组。鼻唇沟表面显示出右鼻下鼻翼曲率向左（-1.99°；P=.02；95％CI-2.61，-0.36）的角度显着降低，并且这些点之间的线性测量值增加（1.01mm；P=.03；95％CI：0.11，1.91）。当比较患侧与非患侧的距离图时，没有发现显着差异（P=.50，95％CI：-0.20，0.29）。
结论：在患有ABG的CUCLAP患者中，肺泡裂隙的闭合不影响鼻内容积，但显著影响外部鼻表面。该过程导致鼻子变宽，因为两个鼻翼曲率都相对于鼻下向尾和横向移动。
方法：回顾性，单臂,队列研究。
方法：机构，三级护理。
方法：单侧完全性唇裂患者，肺泡,和腭（CUCLAP），在9-11岁时接受自体骨移植（ABG）封闭牙槽突裂，使用ABG手术之前和之后一年拍摄的锥形束计算机断层扫描（CBCT）和/或三维（3D）立体摄影测量图像。
方法：CUCLAP患者的ABG治疗。
方法：ABG对鼻内外形态的影响。
结果：共有28例患者（21M/7F，14R/14L）分为内部（CBCT）和外部（3D立体摄影测量）测量亚组。鼻唇沟表面显示出右鼻下鼻翼曲率向左（-1.99°；P=.02；95％CI-2.61，-0.36）的角度显着降低，并且这些点之间的线性测量值增加（1.01mm；P=.03；95％CI：0.11，1.91）。当比较患侧与非患侧的距离图时，没有发现显着差异（P=.50，95％CI：-0.20，0.29）。
结论：在患有ABG的CUCLAP患者中，肺泡裂隙的闭合不影响鼻内容积，但显著影响外部鼻表面。该过程导致鼻子变宽，因为两个鼻翼曲率都相对于鼻下向尾和横向移动。
