PDF(Pubmed)
Abstract：
Kodamaea ohmeri (K. ohmeri) is an ascosporogenic species of yeast that belongs to the genus Ascosporogenous and the family of Saccharomycetaceae. It has recently been found to cause various types of infections, particularly in critically ill immunocompromised patients. The present study describes a case of hospital-acquired pneumonia caused by K. ohmeri during veno-arterial extracorporeal membrane oxygenation. The fungal culture turned negative after the administration of caspofungin and amphotericin B. Extracorporeal membrane oxygenation (ECMO) is an adjunctive medical technique that provides temporary cardiopulmonary support for patients. Previous observations have suggested that the immune function of patients will typically decline during the use of ECMO, rendering infection to be one of the main complications of ECMO. K. ohmeri is a rare pathogenic fungus, particularly in immunocompromised individuals with vascular catheters, while amphotericin B is the most common antifungal therapy administered to treat K. ohmeri infections. It is important to raise awareness of rare fungal infections and actively treat them.
摘要：
Kodamaeaohmeri(K.ohmeri）是酵母的子囊孢子发生物种，属于子囊孢子发生属和酵母菌科。最近发现它会引起各种类型的感染，特别是在重症免疫功能低下患者中。本研究描述了在静脉动脉体外膜氧合过程中由K.ohmeri引起的医院获得性肺炎。卡泊芬净和两性霉素B给药后，真菌培养物变为阴性。体外膜氧合（ECMO）是一种辅助医疗技术，可为患者提供临时心肺支持。以前的观察表明，在使用ECMO期间，患者的免疫功能通常会下降，感染是ECMO的主要并发症之一。K.ohmeri是一种罕见的致病真菌，特别是在有血管导管的免疫功能低下的个体中，而两性霉素B是治疗K.ohmeri感染最常见的抗真菌疗法。重要的是要提高对罕见真菌感染的认识并积极治疗它们。
