Abstract：
Unsafe food causes 600 million cases of foodborne diseases and 420,000 deaths every year. Meanwhile, biological toxins such as poisonous mushrooms, saponins, and aflatoxin can cause significant damage to humans. Therefore, it is particularly important to study foodborne disease outbreaks caused by biotoxins (FDOB). We collected FDOB in Yantai City from 2013 to 2022 and further established a corresponding database. Statistical analysis was carried out according to time, place, pathogen, and contamination of pathogenic factors. There were 128 FDOB, resulting in 417 patients and 6 deaths. The third quarter was a high season for foodborne disease outbreaks, the number of events, patients and deaths accounted for 65.63% (84/128), 55.88% (233/417), and 100% (6/6) of the total number, respectively. The highest number of outbreaks per 10,000 persons was Qixia (0.41), followed by Zhifu (0.36) and Laiyang (0.33). The top three causes of outbreaks were poisonous mushroom toxin, saponins and hemagglutinin, and Lagenaria siceraria (Molina) Standl. Sixty-five (50.78%) outbreaks were attributed to poisonous mushroom toxin, 18 (14.06%) outbreaks to saponin and hemagglutinin, and 12 (9.38%) outbreaks to L. siceraria (Molina) Standl. The largest number of outbreaks, patients and deaths all occurred in families, accounting for 82.81% (106/128) outbreaks, 66.19% (276/417) patients, and 100% (6/6) deaths, respectively. Followed by catering service establishments, accounting for 14.84% (19/128), 30.22% (126/417), and 0% (0/6), respectively. The main poisoning link of outbreaks was ingestion and misuse, accounting for 72.66% (93/128), followed by improper processing, accounting for 20.31% (26/128). It is necessary to carry out targeted family publicity and education, strengthen the integration of medical and prevention, explore innovative monitoring and early warning mechanisms for foodborne diseases, and reduce the occurrence of underreporting of foodborne disease outbreaks.
摘要：
不安全食品每年导致6亿例食源性疾病和42万人死亡。同时,生物毒素，如毒蘑菇，皂苷,黄曲霉毒素会对人类造成重大损害。因此,研究由生物毒素（FDOB）引起的食源性疾病暴发尤为重要。我们收集了烟台市2013-2022年的FDOB，并进一步建立了相应的数据库。按时间进行统计分析,地点,病原体,和致病因素的污染。有128个FDOB,导致417例患者和6例死亡。第三季度是食源性疾病爆发的高发季节,事件的数量，患者和死亡占65.63%(84/128),55.88%（233/417），总数的100%(6/6)，分别。每万人爆发次数最高的是栖霞(0.41),其次是智富(0.36)和莱阳(0.33)。爆发的三大原因是有毒的蘑菇毒素，皂苷和血凝素，和Lagenariasiceraria（Molina）Standl。六十五次(50.78%)疫情被归因于毒蘑菇毒素,18起（14.06%）爆发了皂苷和血凝素，和12（9.38％）的疫情爆发。爆发次数最多的,患者和死亡都发生在家庭中，占82.81%(106/128)的疫情，66.19%（276/417）患者，100%(6/6)死亡，分别。其次是餐饮服务场所，占14.84%(19/128)，30.22%（126/417），和0%(0/6)，分别。疫情的主要中毒环节是摄入和误用，占72.66%(93/128)，其次是不当处理，占20.31%（26/128）。要有针对性地开展家庭宣传教育,加强医疗和预防的结合，探索食源性疾病的创新监测和预警机制，减少食源性疾病暴发漏报的发生。
