Abstract：
Lung cancer has a high morbidity rate worldwide due to its resistance to therapy. So new treatment options are needed to improve the outcomes of lung cancer treatment. This study aimed to evaluate the effectiveness of oncolytic viruses (OVs) as a new type of cancer treatment. In this study, 158 articles from PubMed and Scopus from 1994 to 2022 were reviewed on the effectiveness of OVs in the treatment of lung cancer. The oncolytic properties of eight categories of OVs and their interactions with treatment options were investigated. OVs can be applied as a promising immunotherapy option, as they are reproduced selectively in different types of cancer cells, cause tumor cell lysis and trigger efficient immune responses.
A lot of research has been done to find a cure for lung cancer. Among the methods investigated is the treatment of cancer using a type of virus called an oncolytic virus (OV). Since tumors have unique properties, OVs tend to bind to them and activate immune cells to kill them. This article reviews the combination of OVs with other common cancer treatments which improves their effectiveness, causes fewer reactions and brings better results.
A lot of research has been done to find a cure for lung cancer. Among the methods investigated is the treatment of cancer using a type of virus called an oncolytic virus (OV). Since tumors have unique properties, OVs tend to bind to them and activate immune cells to kill them. This article reviews the combination of OVs with other common cancer treatments which improves their effectiveness, causes fewer reactions and brings better results.
摘要：
由于其对治疗的抗性,肺癌在世界范围内具有高发病率。因此，需要新的治疗方案来改善肺癌治疗的结果。这项研究旨在评估溶瘤病毒（OVs）作为一种新型癌症治疗方法的有效性。在这项研究中,回顾了PubMed和Scopus在1994年至2022年发表的158篇关于OVs在肺癌治疗中的有效性的文章。研究了八类OVs的溶瘤特性及其与治疗方案的相互作用。OVs可以作为一种有前途的免疫疗法，因为它们在不同类型的癌细胞中选择性地繁殖，导致肿瘤细胞裂解并引发有效的免疫反应。
为了找到治疗肺癌的方法，已经进行了大量的研究。研究的方法之一是使用一种称为溶瘤病毒（OV）的病毒治疗癌症。由于肿瘤具有独特的性质，OV倾向于与它们结合并激活免疫细胞以杀死它们。本文回顾了OVs与其他常见癌症治疗方法的结合，以提高其有效性。引起更少的反应，并带来更好的结果。
为了找到治疗肺癌的方法，已经进行了大量的研究。研究的方法之一是使用一种称为溶瘤病毒（OV）的病毒治疗癌症。由于肿瘤具有独特的性质，OV倾向于与它们结合并激活免疫细胞以杀死它们。本文回顾了OVs与其他常见癌症治疗方法的结合，以提高其有效性。引起更少的反应，并带来更好的结果。
