PDF(Pubmed)
Abstract：
OBJECTIVE: To determine the corneal sensitivity recovery period after laser-assisted sub-epithelial keratectomy (LASEK) refractive surgery and investigate the effects of ablation depth on it.
METHODS: In this study examinations were performed on 90 right eyes of 90 people (34 males and 56 females) with an age range of 20-35 and an average of 22.26±3.8 years old. A sensation of 5 corneal regions, including the center and 4 mid-peripheral regions, i.e., nasal, inferior, temporal, and superior, each at a distance of 2 mm from the center of the cornea were measured with a Cochet-Bonnet esthesiometer device in 3-time points including before LASEK, 1 and 3mo after the surgery, respectively. LASEK was performed on individuals with stabilized myopia of -1.00 to -7.00 diopters and astigmatism of less than 2.00 diopters. Furthermore, the individuals were divided into three groups regarding ablation depth.
RESULTS: The highest level of corneal sensitivity before surgery was related to the center of the cornea (59.1±7.76), and the highest level of corneal sensitivity loss was also related to this region. The sensation of all measured corneal regions significantly reduced 1mo postoperatively and returned to their preoperative levels 3mo after surgery (mean of 5 corneal regions in levels of preoperation: 58.2±6.48, 1mo postoperation: 57.3±5.84, 3mo postoperation: 58.2±5.49; P<0.05). A significant relationship was found between ablation depth and corneal sensitivity changes in the center and temporal regions (P<0.05).
CONCLUSIONS: Corneal sensitivity in myopia and low astigmatism decreases after LASEK and reaches the preoperative level within 3mo. The depth of ablation during surgery affected the recovery of corneal sensitivity.
METHODS: In this study examinations were performed on 90 right eyes of 90 people (34 males and 56 females) with an age range of 20-35 and an average of 22.26±3.8 years old. A sensation of 5 corneal regions, including the center and 4 mid-peripheral regions, i.e., nasal, inferior, temporal, and superior, each at a distance of 2 mm from the center of the cornea were measured with a Cochet-Bonnet esthesiometer device in 3-time points including before LASEK, 1 and 3mo after the surgery, respectively. LASEK was performed on individuals with stabilized myopia of -1.00 to -7.00 diopters and astigmatism of less than 2.00 diopters. Furthermore, the individuals were divided into three groups regarding ablation depth.
RESULTS: The highest level of corneal sensitivity before surgery was related to the center of the cornea (59.1±7.76), and the highest level of corneal sensitivity loss was also related to this region. The sensation of all measured corneal regions significantly reduced 1mo postoperatively and returned to their preoperative levels 3mo after surgery (mean of 5 corneal regions in levels of preoperation: 58.2±6.48, 1mo postoperation: 57.3±5.84, 3mo postoperation: 58.2±5.49; P<0.05). A significant relationship was found between ablation depth and corneal sensitivity changes in the center and temporal regions (P<0.05).
CONCLUSIONS: Corneal sensitivity in myopia and low astigmatism decreases after LASEK and reaches the preoperative level within 3mo. The depth of ablation during surgery affected the recovery of corneal sensitivity.
摘要：
目的：确定激光辅助上皮下角膜切除术（LASEK）屈光手术后的角膜敏感性恢复期，并研究消融深度对其的影响。
方法：在这项研究中，对90人（男性34人，女性56人）的90只右眼进行了检查，年龄范围为20-35岁，平均为22.26±3.8岁。5个角膜区域的感觉，包括中心和4个中外围区域，即，鼻部,劣等,temporal,优越,用Cochet-Bonnet美感装置在3个时间点（包括在LASEK之前）测量距角膜中心2mm处的每个距离，手术后1和3个月，分别。对具有-1.00至-7.00屈光度的稳定近视和小于2.00屈光度的散光的个体进行LASEK。此外，根据消融深度将患者分为三组.
结果：术前角膜敏感度最高水平与角膜中心有关（59.1±7.76），角膜敏感性损失的最高水平也与该区域有关。所有测得的角膜区域的感觉均在术后1mo显着降低，并在术后3mo恢复到术前水平（5个角膜区域的平均术前水平：58.2±6.48，术后1mo：57.3±5.84，术后3mo：58.2±5.49；P<0.05）。角膜中心和颞区的消融深度与角膜敏感性变化之间存在显着关系（P<0.05）。
结论：近视和低散光患者的角膜敏感度在LASEK术后降低，并在3mo内达到术前水平。术中消融深度影响角膜敏感性的恢复。
方法：在这项研究中，对90人（男性34人，女性56人）的90只右眼进行了检查，年龄范围为20-35岁，平均为22.26±3.8岁。5个角膜区域的感觉，包括中心和4个中外围区域，即，鼻部,劣等,temporal,优越,用Cochet-Bonnet美感装置在3个时间点（包括在LASEK之前）测量距角膜中心2mm处的每个距离，手术后1和3个月，分别。对具有-1.00至-7.00屈光度的稳定近视和小于2.00屈光度的散光的个体进行LASEK。此外，根据消融深度将患者分为三组.
结果：术前角膜敏感度最高水平与角膜中心有关（59.1±7.76），角膜敏感性损失的最高水平也与该区域有关。所有测得的角膜区域的感觉均在术后1mo显着降低，并在术后3mo恢复到术前水平（5个角膜区域的平均术前水平：58.2±6.48，术后1mo：57.3±5.84，术后3mo：58.2±5.49；P<0.05）。角膜中心和颞区的消融深度与角膜敏感性变化之间存在显着关系（P<0.05）。
结论：近视和低散光患者的角膜敏感度在LASEK术后降低，并在3mo内达到术前水平。术中消融深度影响角膜敏感性的恢复。
