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Abstract：
Ameloblastomas are benign, locally aggressive, odontogenic epithelial neoplasms. We present a patient with a rare granular cell ameloblastoma. This is a case report and literature review conducted from July 2022 to the present. Our 52-year-old male patient presented to the clinic with a several month history of right lower lateral lip swelling and dental complaints. On imaging and physical exam, we noticed a large heterogenous, multiloculated, expansile lesion of the right mandible with several floating teeth. After incisional biopsy confirmed multicystic granular cell ameloblastoma, the patient underwent successful surgical resection and osteocutaneous fibula free-flap reconstruction. At the time of writing this report, 7 years after resection, the patient is alive with no evidence of recurrence. The recognition and treatment of mandibular lesions can represent significant clinical challenges, especially for rarely seen subtypes such as the granular cell ameloblastoma. Special consideration must be given for the identification and treatment of these neoplasms.
摘要：
成釉细胞瘤是良性的，当地的侵略性，牙源性上皮肿瘤。我们介绍了一名罕见的颗粒细胞成釉细胞瘤患者。这是自2022年7月至今的病例报告和文献综述。我们的52岁男性患者出现在诊所，有几个月的右下外侧唇肿胀和牙科投诉的病史。关于成像和身体检查，我们注意到一个大的异质，多位置,右下颌骨扩张性病变，有几颗浮牙。切开活检证实多囊性颗粒细胞成釉细胞瘤后，患者接受了成功的手术切除和腓骨游离皮瓣重建。在撰写本报告时，切除后7年，病人还活着，没有复发的证据。下颌骨病变的识别和治疗可以代表重大的临床挑战，特别是罕见的亚型，如颗粒细胞成釉细胞瘤。必须特别考虑这些肿瘤的识别和治疗。
