关键词: Antiphospholipid antibodies Atrial septal defect Congenital heart disease Heart team Pulmonary artery aneurysm Pulmonary artery thrombosis Pulmonary hypertension Valvular heart disease

来  源:   DOI:10.1016/j.ijscr.2023.109159   PDF(Pubmed)

Abstract:
BACKGROUND: Pulmonary artery thrombosis presents a rare and formidable challenge, especially in individuals with untreated complex congenital heart diseases and concurrent valvular abnormalities.
METHODS: This case details a distinctive instance of pulmonary artery thrombosis in a patient with untreated congenital atrial septal defect, severe pulmonary hypertension, pulmonary aneurysm, valvular heart disease, and triple-positive antiphospholipid antibodies. Collaborative decision-making by a heart team guided the diagnostic and therapeutic processes, resulting in surgical interventions encompassing pulmonary thrombectomy, mitral and tricuspid regurgitation repair, and atrial septal defect closure.
CONCLUSIONS: The case underscores the nuanced management of pulmonary artery thrombosis within the realm of congenital heart disease, highlighting the imperative role of a multidisciplinary approach in achieving accurate diagnoses and timely interventions. The multifaceted treatment strategy implemented further accentuates the need for continual monitoring and personalized interventions in intricate clinical scenarios.
CONCLUSIONS: In conclusion, this case emphasizes the complexity of addressing pulmonary artery thrombosis in the context of congenital heart disease. The collaborative efforts of a multidisciplinary team proved pivotal in navigating diagnostic uncertainties and formulating a tailored treatment plan. Ongoing monitoring and personalized strategies remain crucial for optimizing outcomes in such intricate cases.
摘要:
背景:肺动脉血栓形成是一个罕见而艰巨的挑战,特别是在未经治疗的复杂先天性心脏病和并发瓣膜异常的个体中。
方法:本病例详细介绍了一例未经治疗的先天性房间隔缺损患者的肺动脉血栓形成的特殊情况,严重肺动脉高压,肺动脉瘤,心脏瓣膜病,和三阳性抗磷脂抗体.心脏团队的协作决策指导了诊断和治疗过程,导致包括肺血栓切除术在内的外科手术,二尖瓣和三尖瓣返流修复,房间隔缺损封堵术.
结论:该病例强调了先天性心脏病领域内肺动脉血栓形成的精细管理,强调多学科方法在实现准确诊断和及时干预方面的重要作用。实施的多方面治疗策略进一步强调了在复杂的临床场景中持续监测和个性化干预的需求。
结论:结论:该病例强调了在先天性心脏病背景下解决肺动脉血栓形成的复杂性.多学科团队的合作努力在导航诊断不确定性和制定量身定制的治疗计划方面至关重要。持续的监测和个性化策略对于在这种复杂的情况下优化结果仍然至关重要。
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