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Abstract：
Prostate cancer is the second most common cancer in men. Two common radiotherapy techniques, intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc radiotherapy (VMAT), are used for treatment. This study aimed to compare the two techniques for sparing the bladder and bowel. Computed tomography data from prostate cancer patients were analyzed to define the clinical target volume (CTV) and planning target volume (PTV). Treatment plans were generated with Monte Carlo algorithms, and dosimetric analysis was performed using the Monaco Treatment Planning System (TPS). We compared IMRT and VMAT for prostate cancer PTV coverage (% Ref. Volume), with VMAT showing slightly better coverage (98.885±1.704) compared to IMRT (98.594±0.923). VMAT also demonstrated improved PTV conformity. Additionally, VMAT was superior in sparing the bladder (% V4500<40%), while IMRT performed better in bowel preservation (mean Ref. volume CC<195).
摘要：
前列腺癌是男性第二常见的癌症。两种常见的放射治疗技术，调强放射治疗（IMRT）和体积调强电弧放射治疗（VMAT），用于治疗。这项研究旨在比较保留膀胱和肠的两种技术。分析来自前列腺癌患者的计算机断层扫描数据以定义临床目标体积（CTV）和计划目标体积（PTV）。使用蒙特卡罗算法生成治疗计划，使用摩纳哥治疗计划系统（TPS）进行剂量学分析。我们比较了IMRT和VMAT对前列腺癌PTV覆盖率的影响(%Ref。Volume),与IMRT（98.594±0.923）相比，VMAT显示出略好的覆盖率（98.885±1.704）。VMAT还展示了改进的PTV一致性。此外,VMAT在保留膀胱方面优于（％V4500<40％），而IMRT在肠道保存方面表现更好(平均参考。体积CC<195)。
